DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hs3st-B and Ndst4

DIOPT Version :9

Sequence 1:	NP_001259702.1	Gene:	Hs3st-B / 32918	FlyBaseID:	FBgn0031005	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_072087.2	Gene:	Ndst4 / 64580	MGIID:	1932545	Length:	872	Species:	Mus musculus

Alignment Length:	272	Identity:	92/272 - (33%)
Similarity:	134/272 - (49%)	Gaps:	37/272 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 HLPDTLIIGVKKSGTRALLEFIRLHPDVRA------AGSEVHFFD-RHYQRGLRWYRHHM--PYT 185
            |||..|:||.:|:||.||..|:.:||.:.:      ...||.||: .:|.:|:.||....  |..
Mouse   593 HLPKFLVIGPQKTGTTALYLFLLMHPSIISNLPSPKTFEEVQFFNGNNYHKGIEWYMDFFPTPSN 657

  Fly   186 IEGQITMEKTPSYFVTKEVPQRVYHMNPATKLLIVVRDPVTRAISDYTQAASKKADMKLFEQLAF 250
            |......||:.:||.::|.|:|...:.|..|::.::.||..||.|.|....|.:      :..|.
Mouse   658 ITSDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHE------DPAAL 716

  Fly   251 VNGSYSVVDT-NWGPVKI----------GVYARYLERWLLYFPLSQLLFISGERLIMDPAYEIGR 304
            ....|.|:.| :|.|..:          |.||.::||||.||..||||.|.|::|..|||..:..
Mouse   717 RFNFYEVITTGHWAPPDLKTLQRRCLVPGWYAVHIERWLAYFSTSQLLIIDGQQLRSDPATVMDE 781

  Fly   305 VQDFLGLKRVVTEKHFY-----FNATKGFPCLFKSEARSTPHCLGKTKGRNHPHIDPGAIERLRE 364
            ||.|||    ||..:.|     |:..|||.|......::  .||||:|||.:|.:|..:...|..
Mouse   782 VQKFLG----VTPHYNYSEALTFDPQKGFWCQLLEGGKT--KCLGKSKGRKYPPMDSESRTFLSS 840

  Fly   365 FYRPFNNKFYQL 376
            :||..|.:..:|
Mouse   841 YYRDHNVELSKL 852

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-B	NP_001259702.1	Sulfotransfer_1	131..368	CDD:279075	88/261 (34%)
Ndst4	NP_072087.2	HSNSD	20..505	CDD:288882
		Heparan sulfate N-deacetylase 4	36..588
		Heparan sulfate N-sulfotransferase 4	589..872		92/272 (34%)
		Sulfotransfer_1	594..845	CDD:279075	89/262 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810