DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hs3st-B and Hs3st3b1

DIOPT Version :9

Sequence 1:	NP_001259702.1	Gene:	Hs3st-B / 32918	FlyBaseID:	FBgn0031005	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001178575.1	Gene:	Hs3st3b1 / 303218	RGDID:	1307326	Length:	390	Species:	Rattus norvegicus

Alignment Length:	377	Identity:	193/377 - (51%)
Similarity:	243/377 - (64%)	Gaps:	39/377 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 RSLAIAL-VICVTLVYFSYS-FNAC-------LLASISRSLQQSNLRNLLALTSSPRNETNN--- 80
            |.||:.. ::|:.|..|.|| ..:|       ||.|.||:.....     ||.::| |||:.
  Rat    31 RKLALLFAMLCIWLYMFLYSCAGSCTAAPGLLLLGSGSRATHAQP-----ALITAP-NETSPKMP 89

  Fly    81 ---------AANSSSSNSSSSRNSSSTTGAPPAQTVTSSLDGAPKYQLLRQQGLRPSRHLPDTLI 136
                     .|....:..:.|:...|.........::|...||            .|:.||..:|
  Rat    90 FRAPPANSLVAGKDKTVGAGSQEEQSPEAPDSPSPISSFFSGA------------GSKQLPQAII 142

  Fly   137 IGVKKSGTRALLEFIRLHPDVRAAGSEVHFFDRHYQRGLRWYRHHMPYTIEGQITMEKTPSYFVT 201
            |||||.||||||||:|:||||||.|:|.|||||.|.:||.|||..||.|:|||||||||||||||
  Rat   143 IGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDRSYHKGLAWYRDLMPRTLEGQITMEKTPSYFVT 207

  Fly   202 KEVPQRVYHMNPATKLLIVVRDPVTRAISDYTQAASKKADMKLFEQLAFVNGSYSVVDTNWGPVK 266
            :|.|.|:..|:..|||::|||||||||||||||..||:.|:..||.|.|.|.|..::||:|..::
  Rat   208 REAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPSFESLTFRNRSAGLIDTSWSAIQ 272

  Fly   267 IGVYARYLERWLLYFPLSQLLFISGERLIMDPAYEIGRVQDFLGLKRVVTEKHFYFNATKGFPCL 331
            ||:||::||.||.:|||.|:||:|||||:.|||.|:.||||||||||::|:||||||.|||||||
  Rat   273 IGLYAKHLEPWLRHFPLGQMLFVSGERLVSDPAGELRRVQDFLGLKRIITDKHFYFNQTKGFPCL 337

  Fly   332 FKSEARSTPHCLGKTKGRNHPHIDPGAIERLREFYRPFNNKFYQLTGINFAW 383
            .|:|....||||||||||.||.|....:.:||:||||||.||||:||.:|.|
  Rat   338 KKAEGSGKPHCLGKTKGRAHPTIAREVLRQLRDFYRPFNRKFYQMTGRDFGW 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-B	NP_001259702.1	Sulfotransfer_1	131..368	CDD:279075	154/236 (65%)
Hs3st3b1	NP_001178575.1	Sulfotransfer_1	137..374	CDD:279075	154/236 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	332	1.000	Domainoid score	I1101
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H88576
Inparanoid	1	1.050	368	1.000	Inparanoid score	I2073
OMA	1	1.010	-	-		QHG61370
OrthoDB	1	1.010	-	-		D378919at33208
OrthoFinder	1	1.000	-	-		FOG0000744
OrthoInspector	1	1.000	-	-		otm45601
orthoMCL	1	0.900	-	-		OOG6_106107
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X411
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.740