DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hs3st-B and Hs3st5

DIOPT Version :9

Sequence 1:	NP_001259702.1	Gene:	Hs3st-B / 32918	FlyBaseID:	FBgn0031005	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001099862.1	Gene:	Hs3st5 / 294449	RGDID:	1306379	Length:	346	Species:	Rattus norvegicus

Alignment Length:	287	Identity:	127/287 - (44%)
Similarity:	179/287 - (62%)	Gaps:	27/287 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 SSLDGAPKYQLLRQQGLRPSRHLPDTLIIGVKKSGTRALLEFIRLHPDVRAAGSEVHFF--DRHY 171
            ||.:....:.|::|        ||..:||||:|.|||||||.:.|||.|..|..|:|||  |.:|
  Rat    76 SSKEQVRLHDLVQQ--------LPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENY 132

  Fly   172 QRGLRWYRHHMPYTIEGQITMEKTPSYFVTKEVPQRVYHMNPATKLLIVVRDPVTRAISDYTQAA 236
            .:|:.|||..||::...|||:||:|:||:|:|||:|:|.||.:.|||::||:|.|||||||||..
  Rat   133 AKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLMIVREPTTRAISDYTQVL 197

  Fly   237 S----KKADMKLFEQLAFVNGSYSVVDTNWGPVKIGVYARYLERWLLYFPLSQLLFISGERLIMD 297
            .    |......||:|| ::.:...|:|.:..|:..:|.::|||||.|||:.|...:.|:|||.:
  Rat   198 EGKERKNKTYYKFEKLA-IDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITE 261

  Fly   298 PAYEIGRVQDFLGLKRVVTEKHFYFNATKGFPCL-----FKSEARSTPHCLGKTKGRNHPHIDPG 357
            |..|:..|:.||.|...:::.:.|||||:||.||     |..       ||..:|||.||.:||.
  Rat   262 PLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNK-------CLAGSKGRIHPEVDPS 319

  Fly   358 AIERLREFYRPFNNKFYQLTGINFAWP 384
            .:.:||:|:.|||.||||:||....||
  Rat   320 VVTKLRKFFHPFNQKFYQITGRTLNWP 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-B	NP_001259702.1	Sulfotransfer_1	131..368	CDD:279075	112/247 (45%)
Hs3st5	NP_001099862.1	Sulfotransfer_1	90..330	CDD:279075	112/247 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61370
OrthoDB	1	1.010	-	-		D712400at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830