DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hs3st-B and ndst4

DIOPT Version :9

Sequence 1:	NP_001259702.1	Gene:	Hs3st-B / 32918	FlyBaseID:	FBgn0031005	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	XP_031758874.1	Gene:	ndst4 / 100380006	XenbaseID:	XB-GENE-951845	Length:	873	Species:	Xenopus tropicalis

Alignment Length:	315	Identity:	105/315 - (33%)
Similarity:	145/315 - (46%)	Gaps:	66/315 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 PPAQTVTSSLDGAPKYQLLRQQGLRP--------SRH------------LPDTLIIGVKKSGTRA 146
            ||.|.       |.||..|.|:...|        .||            ||..|:||.:|:||.|
Frog   553 PPIQL-------AHKYFDLFQEQRDPLWQNPCDDRRHRDIWSRDKTCERLPKFLVIGPQKTGTTA 610

  Fly   147 LLEFIRLHPDVRA------AGSEVHFFD-RHYQRGLRWYRHHMPY--TIEGQITMEKTPSYFVTK 202
            |..|:.:||::.:      ...||.||. .:|.:|:.||....||  ........||:.:||.::
Frog   611 LYLFLLMHPNIISNFANPKTFEEVQFFSGNNYHKGIDWYMDSFPYPSNTTSDFLFEKSANYFHSE 675

  Fly   203 EVPQRVYHMNPATKLLIVVRDPVTRAISDYTQAASKKADMKLFEQLAFVNGSYSVV--DTNWGPV 265
            |||:|...:.|..||:.::.||..||.|.|....|.|....|  :.:|    |.|:  |.| .|:
Frog   676 EVPKRAAALLPKAKLITILIDPSDRAYSWYQHQRSHKDPAAL--KFSF----YEVISADQN-APL 733

  Fly   266 KI----------GVYARYLERWLLYFPLSQLLFISGERLIMDPAYEIGRVQDFLGLKRVVTEKHF 320
            ::          |.||.::||||.|||.||||.|.|:.|..:||..:..||.|||    |...:.
Frog   734 ELQMLQRRCLVPGWYASHIERWLAYFPPSQLLIIDGQHLRSEPATVMDEVQKFLG----VFPHYN 794

  Fly   321 Y-----FNATKGFPCLFKSEARSTPHCLGKTKGRNHPHIDPGAIERLREFYRPFN 370
            |     |:..|||.|....|.::  .||||.|||.:|.:|..|...|..:|:..|
Frog   795 YSDALTFDPQKGFWCQLLEEGKT--KCLGKNKGRKYPTMDLEARAFLSTYYQDHN 847

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-B	NP_001259702.1	Sulfotransfer_1	131..368	CDD:279075	93/262 (35%)
ndst4	XP_031758874.1	HSNSD	20..506	CDD:403326
ndst4	XP_031758874.1	Sulfotransfer_1	595..846	CDD:395556	93/263 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910