DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hs3st-B and ndst3

DIOPT Version :9

Sequence 1:	NP_001259702.1	Gene:	Hs3st-B / 32918	FlyBaseID:	FBgn0031005	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	XP_009305879.1	Gene:	ndst3 / 100317129	ZFINID:	ZDB-GENE-090312-199	Length:	874	Species:	Danio rerio

Alignment Length:	360	Identity:	102/360 - (28%)
Similarity:	156/360 - (43%)	Gaps:	86/360 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 SNLRNLLALTSSPRNETNNAANSSSSNSSSSRNSSSTTGAPPAQTVTSSLDGAPKYQLLRQQGLR 126
            :||.|.|...::.|..|                      .||.|.       |.||..|..:...
Zfish   536 TNLANFLKCWTNLRLHT----------------------LPPLQL-------AHKYFTLFPEQRN 571

  Fly   127 P--------SRH------------LPDTLIIGVKKSGTRALLEFIRLHPDVRA------AGSEVH 165
            |        .||            ||..:::|.:|:||.||..|:.:||.:.:      ...||.
Zfish   572 PLWQNPCDDKRHKDIWSKEKTCDRLPKFMVVGPQKTGTTALYLFLIMHPFISSNFPSVKTFEEVQ 636

  Fly   166 FFD-RHYQRGLRWYRHH--MPYTIEGQITMEKTPSYFVTKEVPQRVYHMNPATKLLIVVRDPVTR 227
            ||: .:|.:|:.||...  :|..:......||:.:||.::|.|:|...:.|..|:|.::.:|..|
Zfish   637 FFNTNNYHKGIDWYMEFFPVPSNVSTDFLFEKSANYFPSEETPKRAAALLPKAKILTLLINPSDR 701

  Fly   228 AISDYTQAASKKADMKLFEQLAFVNGSYSVVDT-NWGPVKI----------GVYARYLERWLLYF 281
            |.|.|....:.:....|  |.:|    |.|:.. |..|.::          |:||.:|||||.|:
Zfish   702 AYSWYQHQRAHEDPAAL--QFSF----YEVISADNQAPPELRSLQNRCLIPGLYATHLERWLTYY 760

  Fly   282 PLSQLLFISGERLIMDPAYEIGRVQDFLGLKRVVTEKHFY-----FNATKGFPCLFKSEARSTPH 341
            |.:||:.|.|::|..|||..:..:|.|||    ||..:.|     |:..|||.|......|:  .
Zfish   761 PPNQLMIIDGQQLRNDPAKVMDELQKFLG----VTPYYNYSQALTFDPQKGFWCQLLEGGRT--K 819

  Fly   342 CLGKTKGRNHPHIDPGAIERLREFYRPFNNKFYQL 376
            ||||:|||.:..:|..:...|..:||..|.:..:|
Zfish   820 CLGKSKGRKYSPMDSESRAFLSRYYRDQNIELSKL 854

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hs3st-B	NP_001259702.1	Sulfotransfer_1	131..368	CDD:279075	83/261 (32%)
ndst3	XP_009305879.1	HSNSD	20..507	CDD:288882
ndst3	XP_009305879.1	Sulfotransfer_1	596..845	CDD:279075	82/260 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900