Protein Alignment CG7889 and METTL22

DIOPT Version :10

• Sequence 1: NP_573368.2
• Gene: CG7889 / 32916
• FlyBaseID: FBgn0031003
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: XP_054169869.1
• Gene: METTL22 / 79091
• HGNCID: 28368
• Length: 506
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 60/233 - (25%)
• Similarity: 90/233 - (38%)
• Gaps: 52/233 - (22%)

  Fly    64 HLLLLLGDQEDLHDDIYSSLCGPVAENEASTGSSTYAYKHYLLEPGAHITLR-ESTSFVAEGTTG 127
            |.::|..:::|:             ..|.:.||             .|..:| |.|........|
Human   145 HPMILAQEEDDV-------------LGEEAQGS-------------PHDIIRIEHTMATPLEDVG 183

  Fly   128 LCTWEAALALGDYLLQHRDLVRGKNIVELGAGAGLLGIMLKLPALQLQVGQVLLTDGSEPCVQLM 192
            ...|..||.|.||:|..:||.||...:|||||.||..|:....|     ..|..||.....:.:.
Human   184 KQVWRGALLLADYILFRQDLFRGCTALELGAGTGLASIIAATMA-----RTVYCTDVGADLLSMC 243

  Fly   193 RENISLN-FPDTPKEQMPQAEQLNWAAVS-------EFPW------DSHAKTDLLIAADVIYDDS 243
            :.||:|| ........:.:.::|:|....       .|.|      |.:..|.:|.||:|.|||.
Human   244 QRNIALNSHLAATGGGIVRVKELDWLKDDLCTDPKVPFSWSQEEISDLYDHTTILFAAEVFYDDD 308

  Fly   244 QFDALLGAMDYLYSRRGG------GLETLLASTVRNVD 275
            ..||:...:..|..|...      .:|..|..|:|::|
Human   309 LTDAVFKTLSRLAHRLKNACTAILSVEKRLNFTLRHLD 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7889	NP_573368.2	FAM86	8..83	CDD:464362	3/18 (17%)
		AdoMet_MTases	112..>249	CDD:473071	46/151 (30%)
METTL22	XP_054169869.1	AdoMet_MTases	164..337	CDD:473071	51/190 (27%)