Protein Alignment CG14196 and SLC16A7

DIOPT Version :10

• Sequence 1: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: XP_011537291.1
• Gene: SLC16A7 / 9194
• HGNCID: 10928
• Length: 504
• Species: Homo sapiens
• Alignment Length: 608
• Identity: 106/608 - (17%)
• Similarity: 203/608 - (33%)
• Gaps: 207/608 - (34%)

  Fly    37 PDAGWAWIVCVAAGVS---------NLSIYPCLQQFGFLFRERLSDLGMSSSQITAIINANPAV- 91
            ||.||.|||..||.:|         .::::  .::...:|....|::...||.:.|::.|...:
Human    14 PDGGWGWIVVGAAFISIGFSYAFPKAVTVF--FKEIQQIFHTTYSEIAWISSIMLAVMYAGGRIF 76

  Fly    92 ------------------SACTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVA 138
                              .:|.|.::..:..::..|.|.:||.||....::|.:|..:.:...:.
Human    77 ESFLIFTSLRIQCSFTQSGSCLGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLT 141

  Fly   139 YALLFGFGMGISVSASSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTF---LLTIYGVQGT 200
            ...:.|.|:..::..:...|..||.:||..|.|.:  :.| .|:||..|..|   |...:|.:|:
Human   142 MGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLA--MAG-SPVFLSSLAPFNQYLFNTFGWKGS 203

  Fly   201 TLLFAAISLHSFVCALIYQPVRYHVKPPVEQLADQEQQAEALCAHCSWQQKREPGGIFSSQYLCQ 265
            .|:..::.|::.|...:.:|:..:
Human   204 FLILGSLLLNACVAGSLMRPLGPN----------------------------------------- 227

  Fly   266 DDDAQRPGYEICEPGTPMLSRANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNH 330
                                                    :|.|.||:.
Human   228 ----------------------------------------QTTSKSKNK---------------- 236

  Fly   331 ESDEFLRPNNFRRERVESNLEAKLCCQCSAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLA 395
                                        :.|.|:.::.:|.|                .:.|...
Human   237 ----------------------------TGKTEDDSSPKKIK----------------TKKSTWE 257

  Fly   396 KVVTFFDLDLLRDFTFVNLVAGLTIINFGELNFSILTPFILV-----DFGFDTPQITLAMSLLAG 455
            ||..:.|..|.:...|:..::|..|:..|     ...|.|.:     |.|.|.......:|::|.
Human   258 KVNKYLDFSLFKHRGFLIYLSGNVIMFLG-----FFAPIIFLAPYAKDQGIDEYSAAFLLSVMAF 317

  Fly   456 LDITMRFMV------PFLTEKIPWDNRVFFLIGVVGIALGRTVVACTRSYSLILCSFVWIGLCKG 514
            :|:..|..|      .::..:|.:    ||...::...:...:....:.|:.::...|:.||..|
Human   318 VDMFARPSVGLIANSKYIRPRIQY----FFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFG 378

  Fly   515 -VRTIFWPLIIPGYVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRD---RYDYSVTLHCLNMMS 575
             |.::.:..:: ..|...|...|.||..::.....|:|.|..|.:.|   .|.| :.:.|..::
Human   379 SVSSVLFETLM-DLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKY-MYMSCGAIV- 440

  Fly   576 FVAATSWSL--EALIRRHRRKQR 596
             |||:.|.|  .|:..|...|:|
Human   441 -VAASVWLLIGNAINYRLLAKER 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14196	NP_573367.1	MFS_MCT_SLC16	42..585	CDD:340910	98/590 (17%)
SLC16A7	XP_011537291.1	2A0113	15..484	CDD:273325	105/607 (17%)