Protein Alignment CG14196 and SLC16A4

DIOPT Version :10

• Sequence 1: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_004687.1
• Gene: SLC16A4 / 9122
• HGNCID: 10925
• Length: 487
• Species: Homo sapiens
• Alignment Length: 567
• Identity: 105/567 - (18%)
• Similarity: 203/567 - (35%)
• Gaps: 137/567 - (24%)

  Fly    38 DAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSSQITAIINANPAVSACTGLLNGPM 102
            |.||.|::.:...:.|:.:....:.|...|.....:...:|.||..|.:...::..|.|.|...:
Human    16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGPLVAII 80

  Fly   103 FRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFGMGISVSASSLAINTYFQKKRR 167
            ......:..::.|:.:::|..:::::..:.....|...||.|.|.......:::....||  |:|
Human    81 CDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYF--KKR 143

  Fly   168 RAAGFSWTITGLGPIF-LPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIYQPVRYHVKPPVEQ 231
            .|...:...:|:|..| |.....||:.:|...|..:||.||:|:....:::.:|:  |:|.  |.
Human   144 LALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALILFGAIALNLVPSSMLLRPI--HIKS--EN 204

  Fly   232 LADQEQQAEALCAHCSWQQKREPGGIFSSQYLCQDDDAQRPGYEICEPGTPMLSRANDGWYGSRL 296
            .:..:.:..:|.||.......|.....:.:...:|...|:.|.
Human   205 NSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGL---------------------- 247

  Fly   297 SLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNNFRRERVESNLEAKLCCQCSAK 361
                         .||:|..:|           ::|:||....|..|..::|:.|:......|.|
Human   248 -------------PSKNLTVSQ-----------NQSEEFYNGPNRNRLLLKSDEESDKVISWSCK 288

  Fly   362 REEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRD-----FTFVNLVAGLTII 421
            :                                     .||:.|.|:     ||:..|::
Human   289 Q-------------------------------------LFDISLFRNPFFYIFTWSFLLS----- 311

  Fly   422 NFGELNFSILTPFILV----DFGFDTPQITLAMSLLAGLDITMRFMVPFLTE-----KIPWDNRV 477
               :|.:.|.| |.||    ..|.|....:..:|:...|:...:.:..::.:     |..:....
Human   312 ---QLAYFIPT-FHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKKYHYHKSY 372

  Fly   478 FFLIGVVGIALGRTVVACTRSYSLILCSFVWIGLCKGVRTIFWPLIIPGYVPLNRLPGAS---GL 539
            ..|.|:..:     :.....::.|::...:...:..|.   :..||:|..|.|.|....:   ||
Human   373 LILCGITNL-----LAPLATTFPLLMTYTICFAIFAGG---YLALILPVLVDLCRNSTVNRFLGL 429

  Fly   540 QLLISGLFTLIGGPFVGLVRDRYDYSVT----------LHCLNMMSF 576
            ....:|:..|.|.|..|.:   |||:.|          .:.|:.:||
Human   430 ASFFAGMAVLSGPPIAGWL---YDYTQTYNGSFYFSGICYLLSSVSF 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14196	NP_573367.1	MFS_MCT_SLC16	42..585	CDD:340910	102/563 (18%)
SLC16A4	NP_004687.1	MFS_MCT5	20..481	CDD:340979	102/563 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..250		7/78 (9%)