Protein Alignment CG14196 and SLC16A6

DIOPT Version :10

• Sequence 1: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: XP_024306789.2
• Gene: SLC16A6 / 9120
• HGNCID: 10927
• Length: 542
• Species: Homo sapiens
• Alignment Length: 598
• Identity: 115/598 - (19%)
• Similarity: 210/598 - (35%)
• Gaps: 144/598 - (24%)

  Fly     9 TTRPLPRVSRARYYNKHDKSDLGDDFVAPDAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSD 73
            |...|...|:|..|.:           .||.||.|.|.|:.....:..|..::.||..|.:.:..
Human    21 TQNKLKLCSKANVYTE-----------VPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDS 74

  Fly    74 LGMSSSQITAIINANPAVSACTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVA 138
            ...|:|:|:.||:....|...:..|...:..||..|.|.|.|.||:|..::..:|.:......||
Human    75 FNESNSRISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVA 139

  Fly   139 YALLFGFGMGISVSASSLAINTYFQKKRR-----RAAGFSWTITGLGPIFLPHLVTFLLTIYGVQ 198
            ..::.|.|...|...:...::.||.|:|.     .:.|..:.:....|..:.     |....|.:
Human   140 IGIISGLGYCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMA-----LKERIGWR 199

  Fly   199 GTTLLFAAISLHSFVCALIYQPVRYHVKPPVE-QLADQEQQAEALCAHCSWQQKREPGGIFSSQY 262
            .:.|....:.|:..:...:.:|:  .::.|.. ::..||.:.||                   ||
Human   200 YSLLFVGLLQLNIVIFGALLRPI--FIRGPASPKIVIQENRKEA-------------------QY 243

  Fly   263 LCQDDDAQRPGYEICEPGTPMLSRANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEE 327
            :.:::.                         :|.|:.|       |.|..:|..:
Human   244 MLENEK-------------------------TRTSIDS-------IDSGVELTTS---------- 266

  Fly   328 QNHESDEFLRPNNFRRERVESNLEAKLCCQCSAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMS 392
                      |.|.                     ..|.|...|.:|:.::..::::|...
Human   267 ----------PKNV---------------------PTHTNLELEPKADMQQVLVKTSPRPS---- 296

  Fly   393 FLAKVVTFFDLDLLRDFTFV-NLVAGLTIINFGELNFSILTPFIL---VDFGFDTPQITLAMSLL 453
              .|.....|..:|::.:|: ..:.||    |..|.|...:.:|:   :..|.|..:....:|.:
Human   297 --EKKAPLLDFSILKEKSFICYALFGL----FATLGFFAPSLYIIPLGISLGIDQDRAAFLLSTM 355

  Fly   454 AGLDITMRFMVPFLTEKIPWDNRVFFLIGVVGIALGR-TVVACTRSYSLILCSFVW---IGLCKG 514
            |..::..|....|:..:.|.......||.|:.:.:.. .....|..:.|:.||..:   :|...|
Human   356 AIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGG 420

  Fly   515 VRTIFWPLII-PGYVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRDRYD-YSVTLH-CLNMMSF 576
            ...   ||:. ...|.:.::..|:|:.:.|..:..|.|.|..||:.|:.. ||...: |...|:.
Human   421 THI---PLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMAL 482

  Fly   577 VAATSWSLEALIR 589
            .|...    ||:|
Human   483 AAVCL----ALVR 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14196	NP_573367.1	MFS_MCT_SLC16	42..585	CDD:340910	103/559 (18%)
SLC16A6	XP_024306789.2	MFS_MCT7	43..491	CDD:340980	105/563 (19%)