Protein Alignment CG14196 and SLC16A2

DIOPT Version :10

• Sequence 1: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_006508.2
• Gene: SLC16A2 / 6567
• HGNCID: 10923
• Length: 539
• Species: Homo sapiens
• Alignment Length: 596
• Identity: 103/596 - (17%)
• Similarity: 180/596 - (30%)
• Gaps: 210/596 - (35%)

  Fly    34 FVAPDAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSSQIT------------AIIN 86
            |..|:.|:.|:|..||...|.||:......|.|:...|.:....:.|:.            .|..
Human    92 FQPPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFF 156

  Fly    87 ANPAVSACTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFGMGISV 151
            .:|.||..|.        |...|..|.||:.:....|..::|..:.......|.:|||.|...:.
Human   157 CSPIVSIFTD--------RLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAF 213

  Fly   152 SASSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQ-GTTLLFAAISLHSFVCA 215
            ..|.:.:..|||::...|.|    :...|.........||:.:.|.: .....|..:|...||..
Human   214 QPSLVILGHYFQRRLGLANG----VVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVLM 274

  Fly   216 LIYQPVRYHVKPPVEQLADQEQQAEALCAHCSWQQKREPGGIFSSQYLCQDDDAQRPGYEICEPG 280
            |:....|
Human   275 LLSLTYR---------------------------------------------------------- 281

  Fly   281 TPMLSRANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNNFRRER 345
             |:|..:.|         |..:...||
Human   282 -PLLPSSQD---------TPSKRGVRT-------------------------------------- 298

  Fly   346 VESNLEAKLCCQCSAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRDFT 410
                                                    ||   ..|||::..:|::.:.|..|
Human   299 ----------------------------------------LH---QRFLAQLRKYFNMRVFRQRT 320

  Fly   411 FVNLVAGLTIINFGELNFSILTPFI----LVDFGF----DTPQITLAMSLLAGLDITMRFMVPFL 467
            :.....|:.....|     ...|::    .|:..|    :|..:.:.:...:||.   |.:...:
Human   321 YRIWAFGIAAAALG-----YFVPYVHLMKYVEEEFSEIKETWVLLVCIGATSGLG---RLVSGHI 377

  Fly   468 TEKIPWDNRV------FFLIGVVGIALGRTVVACTRSYS--LILCSFVWIGLCKG-VRTIFWPLI 523
            ::.||...::      |.|:|::.:     ::...|.:.  :::|.|  :|||.| ..||..|:.
Human   378 SDSIPGLKKIYLQVLSFLLLGLMSM-----MIPLCRDFGGLIVVCLF--LGLCDGFFITIMAPIA 435

  Fly   524 IPGYVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRDRY-DYSVTLHCLNMMSFVAATSWSLEAL 587
            .....|: :...|.|..|.:..|..:.|.|..||:|:.: ||.|..:...:...:.|.......|
Human   436 FELVGPM-QASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPL 499

  Fly   588 I--RRHRRKQR 596
            :  |..:::||
Human   500 MHQRMFKKEQR 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14196	NP_573367.1	MFS_MCT_SLC16	42..585	CDD:340910	96/573 (17%)
SLC16A2	NP_006508.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92		103/596 (17%)
		MFS_MCT8_10	100..498	CDD:340978	96/574 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	508..539		2/3 (67%)