Protein Alignment CG14196 and Slc16a8

DIOPT Version :10

• Sequence 1: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_065262.1
• Gene: Slc16a8 / 57274
• MGIID: 1929519
• Length: 492
• Species: Mus musculus
• Alignment Length: 540
• Identity: 107/540 - (19%)
• Similarity: 167/540 - (30%)
• Gaps: 188/540 - (34%)

  Fly    37 PDAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSSQITAIINANPAVSACTGLLNGP 101
            ||.||.|:|..|..|.....|...:.....|||...|.|...|....:.:...|:...||.|:..
Mouse    13 PDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRELKRDFGAGYSDTAWVSSIMLAMLYGTGPLSSI 77

  Fly   102 MFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFGMGISVSASSLAINTYFQKKR 166
            :..||..|.|.:||.||.|..:||.:|....:...:...:|.|.|:.::...|.:.:..||:::|
Mouse    78 LVTRFGCRPVMLAGGLLASAGMILASFASRLVELYLTAGVLTGLGLALNFQPSLIMLGLYFERRR 142

  Fly   167 RRAAGFSWTITGLGPIFLPHLV---TFLLTIYGVQGTTLLFAAISLHSFVCALIYQPVRYHVKPP 228
            ..|.|.:   ....|:||..|.   ..|...:|.:|..|||..:.||...|..:       ::||
Mouse   143 PLANGLA---AAGSPVFLSMLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAV-------MRPP 197

  Fly   229 VEQLADQEQQAEALCAHCSWQQKREPGGIFSSQYLCQDDDAQRPGYEICEPGTPMLSRANDGWYG 293
                                                              ||.|
Mouse   198 --------------------------------------------------PGPP----------- 201

  Fly   294 SRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNNFRRERVESNLEAKLCCQC 358
                                         |..:...|....       ||.|:   |:..:|
Mouse   202 -----------------------------PRRDPSPHGGPA-------RRRRL---LDVAVC--- 224

  Fly   359 SAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRDFTFVNLVAGLTIINF 423
                                          ...:|:..|||.| |..|..|     |..:.::|:
Mouse   225 ------------------------------TDRAFVVYVVTKF-LMALGLF-----VPAILLVNY 253

  Fly   424 GELNFSILTPFILVDFGFDTPQITLAMSLLAGLDIT-------------MRFMVPFLTEKIPWDN 475
            .:            |.|....:....:|::..:||.             :|..||:|
Mouse   254 AK------------DAGVPDAEAAFLLSIVGFVDIVARPACGALAGLGRLRPHVPYL-------- 298

  Fly   476 RVFFLIGVVGIALGRTVVACTRSYSLILCSFVWIGLCKGVRTIFWPLIIPGYVPLNRLPGASGLQ 540
               |.:.::...|...:.|..|||..::...:..||..|:.......::...|...|.|.|.||.
Mouse   299 ---FSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMATVGAPRFPSALGLV 360

  Fly   541 LLISGLFTLIGGPFVGLVRD 560
            ||:..:..|||.|..|.:.|
Mouse   361 LLVEAVAVLIGPPSAGRLVD 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14196	NP_573367.1	MFS_MCT_SLC16	42..585	CDD:340910	103/535 (19%)
Slc16a8	NP_065262.1	2A0113	14..440	CDD:273325	106/539 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..492
		Basolateral sorting signal. /evidence=ECO:0000250|UniProtKB:O95907	426..460
		Basolateral sorting signal. /evidence=ECO:0000250|UniProtKB:O95907	461..482