Protein Alignment CG14196 and slc16a12

DIOPT Version :10

• Sequence 1: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_989310.1
• Gene: slc16a12 / 394932
• XenbaseID: XB-GENE-1012784
• Length: 473
• Species: Xenopus tropicalis
• Alignment Length: 592
• Identity: 111/592 - (18%)
• Similarity: 194/592 - (32%)
• Gaps: 189/592 - (31%)

  Fly    37 PDAGWAWIV---CVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSSQITAIINANPAVSACTGLL 98
            ||.||.|::   |....|...::..|:..|...|:...:.....::.|.:|::       |:.:|
 Frog    13 PDGGWGWMIVIGCFFVTVCTRAVTRCISIFFVEFQSYFAQDYARTAWIHSIVD-------CSTML 70

  Fly    99 NGP----MFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYM-VAYALLFGFGMGISVSASSLAI 158
            ..|    :...|:.:...:.|.:|.|..|:|::|. |.|.|: :...:|.|.|..:..|.:...:
 Frog    71 CAPIGSYVSNHFSCQVGIILGGVLASTGLVLSSFA-TSLEYLYLTLGVLTGLGFALCYSPAIAMV 134

  Fly   159 NTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIYQPV-- 221
            ..||:|::..|.|.:.:.:|:|...|..:|..|:..:..:|..|:......:..||..:.:|:
 Frog   135 GKYFEKRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVSNLCVCGALMRPITL 199

  Fly   222 -----RYHVKPPVEQLADQEQQAEALCAHCSWQQKREPGGIFSSQYLCQDDDAQRPGYEICEPGT 281
                 .|.:|.  ||:.::..|:..|.:.||      |        ||||
 Frog   200 KEDSLHYPLKQ--EQMENEPTQSGRLDSSCS------P--------LCQD--------------- 233

  Fly   282 PMLSRANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNNFRRERV 346
                                                    |      :|
 Frog   234 ----------------------------------------C------SH---------------- 236

  Fly   347 ESNLEAKLCCQCSAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRDFTF 411
                  |..|.|:.|                            :.|||.|.            .|
 Frog   237 ------KRLCYCTKK----------------------------EYSFLLKP------------KF 255

  Fly   412 VNLVAGLTIINFG-ELNFSILTPFILVDFGFDTPQITLAMSLLAGLDITMRFMVPFLTEKIPWDN 475
            :.|......:.:| ...|..|.|:.| :.|....:....||:|..:||.......::|     |.
 Frog   256 MVLAVSFLFLAYGCSPPFVYLVPYAL-NVGVSNQEAAFLMSILGIIDIVGNITFGWVT-----DT 314

  Fly   476 RVF-------FLIGVVGIALGRTVVAC------TRSYSLILCSFVWIGLCKGVRTIFWPLIIPGY 527
            |..       :|     ||:|...:.|      || :.|::...|..|...|......|::....
 Frog   315 RFLKKHRYCCYL-----IAVGLDGLCCLFLPILTR-FQLLVPFSVMFGYFDGAYVALIPVVTGDV 373

  Fly   528 VPLNRLPGASGLQLLISGLFTLIGGPFVG-LVRDRYDYSVTLHCLNMMSFVAATSWSLEALIRRH 591
            |..:.|..|.|:...:..:..|:..|..| ||....||:.............|...:|..:|.|.
 Frog   374 VGTSSLSSALGVVFFLHAVPYLVSPPIAGWLVDTTGDYTAAFLLSGFSMIFCAVLLALAKIINRI 438

  Fly   592 RRKQRLV 598
            :::.:.|
 Frog   439 KKRPKAV 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14196	NP_573367.1	MFS_MCT_SLC16	42..585	CDD:340910	103/572 (18%)
slc16a12	NP_989310.1	MFS_MCT12	18..433	CDD:340982	104/573 (18%)