Protein Alignment CG14196 and SLC16A12

DIOPT Version :10

• Sequence 1: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_998771.3
• Gene: SLC16A12 / 387700
• HGNCID: 23094
• Length: 516
• Species: Homo sapiens
• Alignment Length: 616
• Identity: 113/616 - (18%)
• Similarity: 202/616 - (32%)
• Gaps: 185/616 - (30%)

  Fly     1 MEKKVYQDTTRPLPRVSRARYYNKHDKSDLGDDFVAPDAGWAWIV---CVAAGVSNLSIYPCLQQ 62
            :|:...::..:.:.:|:|||..:            .||.||.|::   |....:...::..|:..
Human    19 LEQPGKEEKRKTMAKVNRARSTS------------PPDGGWGWMIVAGCFLVTICTRAVTRCISI 71

  Fly    63 FGFLFRERLSDLGMSSSQITAIINANPAVSACTGLLNGPM----FRRFTFRQVAMAGSLLISGSL 123
            |...|:...:.....::.|.:|::       |..:|..|:    ....:.:...|.|.||.|..|
Human    72 FFVEFQTYFTQDYAQTAWIHSIVD-------CVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGL 129

  Fly   124 ILTAFCETFLSYMVAYALLFGFGMGISVSASSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLV 188
            ||::|..:.....:...:|.|.|..:..|.:...:..||.:::..|.|.:.:.:|:|...|..:|
Human   130 ILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVV 194

  Fly   189 TFLLTIYGVQGTTLLFAAISLHSFVCALIYQPVRY---HVKPPVEQLADQEQQAEALCAHCSWQQ 250
            ..|:..:..:|..|:.....|:..||..:.:|:..   |..|        ||
Human   195 QLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTP--------EQ------------- 238

  Fly   251 KREPGGIFSSQYLC--QDDDAQRPGYEICEPGTPMLSRANDGWYGSRLSLTSGRLRFRTISSSKD 313
                      .::|  |.:|.:|     ..|.:               |||            |:
Human   239 ----------NHVCRTQKEDIKR-----VSPYS---------------SLT------------KE 261

  Fly   314 LEQTQRLHCPISEEQNHESDEFLRPNNFRRERVESNLEAKLCCQCSAKREEHNNNRKEKEAEAEE 378
            ..||                                      |.|...::|:
Human   262 WAQT--------------------------------------CLCCCLQQEY------------- 275

  Fly   379 AGMESAPLHDPQMSFLAKVVTFFDLDLLRDFTFVNLVAGLTIINFG-ELNFSILTPFILVDFGFD 442
                         |||          |:.|  ||.|...:..:.:| ...|..|.|:.| ..|..
Human   276 -------------SFL----------LMSD--FVVLAVSVLFMAYGCSPLFVYLVPYAL-SVGVS 314

  Fly   443 TPQITLAMSLLAGLDITMRFMVPFLTEKIPWDNRVF----FLIGVVGIALGRTVVACTRSYSLIL 503
            ..|....||:|..:||.......:||::....|..:    |.:|:.|:..  ..:...:|..|::
Human   315 HQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCY--LCLPMLQSLPLLV 377

  Fly   504 ---CSFVWIGLCKGVRTIFWPLIIPGYVPLNRLPGASGLQLLISGLFTLIGGPFVG-LVRDRYDY 564
               |:|   |...|......|::....|....|..|.|:...:..:..|:..|..| ||.....|
Human   378 PFSCTF---GYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSY 439

  Fly   565 SVTLHCLNMMSFVAATSWSLEALIRRHRRKQ 595
            :............::.......||:|.|:.|
Human   440 TAAFLLCGFSMIFSSVLLGFARLIKRMRKTQ 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14196	NP_573367.1	MFS_MCT_SLC16	42..585	CDD:340910	99/563 (18%)
SLC16A12	NP_998771.3	MFS_MCT12	48..461	CDD:340982	99/564 (18%)