Protein Alignment CG14196 and chk

DIOPT Version :10

• Sequence 1: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_610230.3
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Alignment Length: 740
• Identity: 142/740 - (19%)
• Similarity: 257/740 - (34%)
• Gaps: 238/740 - (32%)

  Fly    37 PDAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSSQ---ITAIINANPAVSACTGLL 98
            ||.|:.|:|..|:.|.:|........||.:..|.|...|.|:|:   |:::..:.|       ||
  Fly   133 PDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISSLFFSVP-------LL 190

  Fly    99 NGPMFR----RFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFGMGISVSASSLAIN 159
            .||::.    ::..|::.:.|.::.:....|::||.:....||.:.::.|.|:||....:.::|.
  Fly   191 MGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSIA 255

  Fly   160 TYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIYQPVRYH 224
            .:|.|||..|.|...:.||:|......|.::|:..||.:|.||:.....|::.||..:.:...:.
  Fly   256 FWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMRDPDWL 320

  Fly   225 VK---------------------PPVEQLADQEQQAEALCAHC-------SWQQ---------KR 252
            ::                     ..:::|.|.....||:....       :.||         ||
  Fly   321 IEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPLDSALKR 385

  Fly   253 EPGGIFSSQYL-CQDDDAQRPGYEICE----------------------------------PGTP 282
            ....||...:| .|:.|:      |||                                  |.|.
  Fly   386 YRSEIFLPTFLSTQELDS------ICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPSTA 444

  Fly   283 MLSRANDGWYG------------------SRLSLTSGRLRFRT----ISSSKDLEQTQR------ 319
            ::...:|...|                  ..||.:..|...||    :.||.:...||:
  Fly   445 VIGSPDDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHASSRY 509

  Fly   320 -----------------------------------LHCPISEEQNH---ESDEFLRPNNFRRERV 346
                                               :||..|:::..   |....:||........
  Fly   510 SLNENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIPEQ 574

  Fly   347 ESNLEAKLCCQ--------------CSAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKV 397
            |.::.::|..:              .|.|...|.:|.:...:......::...:|...:.:...:
  Fly   575 EQSVNSELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRGAM 639

  Fly   398 VTFFDLDLLRDFTFVNLVA-GLTII----------NFGELNFSILTPFILVDFGFDTPQITLAMS 451
            :..... .||..:..|:.. .:|.|          ||.:...||....:.:|..|       |:.
  Fly   640 LNTHRY-RLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMKF-------ALF 696

  Fly   452 LLAGLDITMRFMVPFL-----TEKIPWD-NRVFFLIGVVGIALGRTVVACTRSY-------SLIL 503
            .|:.|.:.:.|::|:|     .::..:| ::...||..||||  :||......|       ::.:
  Fly   697 NLSTLFLFIWFIIPYLYLPDYMKQYKYDVSQSAELISDVGIA--QTVGMIGLGYLGDLSWMNINI 759

  Fly   504 CSFVWIGLCKGVRTIFWPLIIPGY----------------------------VPLNRLPGASGLQ 540
            |..:.:.:| |....|.||:|..|                            |.|:....|.||.
  Fly   760 CYSLCMLVC-GASVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILVSIVDLDDFTCAYGLV 823

  Fly   541 LLISGLFTLIGGPFVGLVRDRYDYS 565
            ||:.|:..:.|.|..|::   |:|:
  Fly   824 LLVQGVGMIAGPPIAGVI---YEYT 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14196	NP_573367.1	MFS_MCT_SLC16	42..585	CDD:340910	139/735 (19%)
chk	NP_610230.3	MFS_MCT_SLC16	138..>315	CDD:340910	49/183 (27%)
		MFS	<687..869	CDD:475125	39/172 (23%)