Protein Alignment CG14196 and Slc16a4

DIOPT Version :10

• Sequence 1: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001013935.1
• Gene: Slc16a4 / 295356
• RGDID: 1359655
• Length: 500
• Species: Rattus norvegicus
• Alignment Length: 616
• Identity: 118/616 - (19%)
• Similarity: 206/616 - (33%)
• Gaps: 209/616 - (33%)

  Fly    38 DAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSSQITAIINANPAVSACTGLLNGPM 102
            |.||.|:|.:...:.|:.:....:.|...|.....:...:|.||..|.:...::....|.|...:
  Rat    16 DGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFSAGPLAAII 80

  Fly   103 FRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFGMGISVSASSLAINTYFQKKRR 167
            ...|..:..::.|:.|:||..:::::........|...||.|.|.......:::.|..||:|:
  Rat    81 CDIFGEKTTSILGTFLVSGGYLISSWATGIPFLCVTMGLLPGLGSAFLYQVAAVVITKYFKKR-- 143

  Fly   168 RAAGFSWTI--TGLGPIFLPHLVTF---LLTIYGVQGTTLLFAAISLHSFVCALIYQPVRYHVKP 227
              .|.|..|  :|:|..||  |..|   |:.:|...|..:||.||:|:....:::.:||  |::.
  Rat   144 --LGLSTAIARSGMGLTFL--LAPFTKLLIDLYDWTGALILFGAIALNLVPSSMLLRPV--HIQS 202

  Fly   228 PVEQLADQEQQAEALCA------HCSWQQKREPGGIFSSQYLCQDDDAQRPGYEICEPGTPMLSR 286
              :..:|.:.:...|.|      |    :...|....:.:.|.:|...::.|    :|.|
  Rat   203 --DSNSDIKNKGSILSATGPELSH----KTETPNRNKAQESLIKDSAVKKSG----QPTT----- 252

  Fly   287 ANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNN--FRRERVESN 349
                      :||....:...||:                 :.|.:...|..|:  ::::.|..|
  Rat   253 ----------TLTVLENQIEEIST-----------------RPHRNRPLLMSNDKTYKKKFVSWN 290

  Fly   350 LEAKLCCQCSAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRDFTFVNL 414
            .:.||                                              .|:.|.|:..|
  Rat   291 CKEKL----------------------------------------------LDISLFRNPFF--- 306

  Fly   415 VAGLTIINFGELNFSILTPFILVDFGFDTPQITL-AMSLLAGLDITMRFMVPFLTEKIPWDNRVF 478
                         :.....|:|....:..|...| |.:...|:||.                ...
  Rat   307 -------------YIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIM----------------DAS 342

  Fly   479 FLIGVVGIALGRTVVACTRSYSLILCSFV----WIG----------LCKGVR------------- 516
            :|:.|.||         |.:.|.::..::    ||.          || ||.
  Rat   343 YLVSVAGI---------TETVSQLISGWIADQNWIKKYQYHKAYLILC-GVTNLLAPLATTFPLL 397

  Fly   517 ---TIFWPLIIPGYVPL-----------NRLPGASGLQLLISGLFTLIGGPFVGLVRDRYDY--- 564
               |||:.:...||:.|           :|:....|.....:|:..|.|.|..|.:   |||
  Rat   398 MAYTIFFAIFAGGYLALILPVLVDLSKNSRVHRFLGYASFFAGMAVLSGPPIAGWI---YDYTQT 459

  Fly   565 -------SVTLHCLNMMS--FV-AATSWSLE 585
                   |.|.:.|:.:|  || .|..|.|:
  Rat   460 YVGSFYFSGTCYILSSVSLFFVPLAERWKLK 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14196	NP_573367.1	MFS_MCT_SLC16	42..585	CDD:340910	114/610 (19%)
Slc16a4	NP_001013935.1	MFS_MCT5	20..486	CDD:340979	113/606 (19%)