Protein Alignment CG14196 and Slc16a1

DIOPT Version :10

• Sequence 1: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_036848.1
• Gene: Slc16a1 / 25027
• RGDID: 3690
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 599
• Identity: 123/599 - (20%)
• Similarity: 200/599 - (33%)
• Gaps: 193/599 - (32%)

  Fly    34 FVAPDAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSSQITAIINANPAVSACTGLL 98
            :..||.||.|.|.|.|.:|....|...:.....|:|.......::|:::.|.:...||....|.:
  Rat    11 YTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPI 75

  Fly    99 NGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFGMGISVSASSLAINTYFQ 163
            :..:..::..|.|.:||..|....||..:||.|.........::.|.|:..:::.:...|..||.
  Rat    76 SSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFY 140

  Fly   164 KKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIYQPVRYHVKPP 228
            |||..|.|.:  :.| .|:||..|.                                       |
  Rat   141 KKRPLANGLA--MAG-SPVFLSTLA---------------------------------------P 163

  Fly   229 VEQLADQEQQAEALCAHCSWQQKREPGGIFSSQYLCQDDDAQRPGYEICEPGTPMLSRANDGWYG 293
            :.|..                     .|||                               ||.|
  Rat   164 LNQAF---------------------FGIF-------------------------------GWRG 176

  Fly   294 SRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNNFRRERVESNLEAKLCCQC 358
            |.|.| .|.|                |:|.:       :...:||...::.:||     ||
  Rat   177 SFLIL-GGLL----------------LNCCV-------AGSLMRPIGPQQGKVE-----KL---- 208

  Fly   359 SAKREEHNNNRKEKEAEAEEAGMESA--------PLHDPQMSFLAKVVTFFDLDLLRDFTFVNLV 415
                       |.||: .:|||...|        |..: ::|....|..|.||.|.....|:..:
  Rat   209 -----------KSKES-LQEAGKSDANTDLIGGSPKGE-KLSVFQTVNKFLDLSLFTHRGFLLYL 260

  Fly   416 AGLTIINFGELNFSILTPFI-LVDFG----FDTPQITLAMSLLAGLDITMRFMVPFLTEKIPWDN 475
            :|..::.||     :.||.: |.::|    |.:.:....:|:||.:|:..|..:. |.....|..
  Rat   261 SGNVVMFFG-----LFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMG-LAANTRWIR 319

  Fly   476 ---RVFFLIGVVGIALGRTVVACTRSYSLILCSFVWIGLC--KGV---------RTIFWPLIIPG 526
               :.||...||...:...:...:.:|         :|.|  .||         ..:|..|:  .
  Rat   320 PRVQYFFAASVVANGVCHLLAPLSTTY---------VGFCIYAGVFGFAFGWLSSVLFETLM--D 373

  Fly   527 YVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRDRY-DYSVTLHCLNMMSFVA--------ATSW 582
            .|...|...|.||..::.....|:|.|.:|.:.|.| ||..|.....::..:|        ..::
  Rat   374 LVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINY 438

  Fly   583 SLEALIRRHRRKQR 596
            .|.|..::...|:|
  Rat   439 RLVAKEQKAEEKKR 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14196	NP_573367.1	MFS_MCT_SLC16	42..585	CDD:340910	115/578 (20%)
Slc16a1	NP_036848.1	2A0113	1..462	CDD:273325	123/599 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	446..494		2/7 (29%)