Protein Alignment CG14196 and mct-4

DIOPT Version :10

• Sequence 1: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_001041267.1
• Gene: mct-4 / 180766
• WormBaseID: WBGene00003986
• Length: 777
• Species: Caenorhabditis elegans
• Alignment Length: 660
• Identity: 139/660 - (21%)
• Similarity: 240/660 - (36%)
• Gaps: 192/660 - (29%)

  Fly    36 APDAGWAWIVCVAAGVSNL---SIYPCLQQFGFLFRERLSDLGMSSSQITAIINANPAVSACTGL 97
            |||.|:.|::..||.:|||   .|.....:|...::||..:    |..:|..|.   ::...|.|
 Worm    69 APDGGYGWVIVFAAFMSNLVVDGISTAFSEFKQSYKERYQE----SDGLTVFIG---SLIIGTYL 126

  Fly    98 LNGPMF----RRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFGMGISVSASSLAI 158
            |.||:.    .::..|.|.|||.|:...:.::.........:|:.|.::.|.|.|:....:.:.:
 Worm   127 LVGPLVSALCNKYEQRYVVMAGGLISGIAFMIAPASPNIYVFMLIYGVMGGLGFGMIYLPAIVVV 191

  Fly   159 NTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIYQPVRY 223
            ..||..||..|.|.|...:|:|...:|.:....:...|.|.|..:.|.:.........:|:|:
 Worm   192 GFYFDSKRAMATGISVAGSGVGTFLVPLICQVCIANLGWQKTIWVLAVMIFSCVFYGYLYRPL-- 254

  Fly   224 HVKPPVE--QLADQEQQA-------------EALCAHCSWQQKREPGGIFSSQYLCQDDDAQRPG 273
               |.|:  ::.|||.:.             ||:.:....:......|....:.:.|:.:.||
 Worm   255 ---PMVDLNEIRDQEMEPLRQALSKVEDDEDEAVESPHPNRSTSAASGAIEDEAVSQNPEVQR-- 314

  Fly   274 YEICEPGTPMLSRANDGWYGSRL---------SLTSGRLRFRTISSSK-----------DLEQTQ 318
                     :.|...:|..||..         |.|:.|.|..|::|:.           :|....
 Worm   315 ---------LRSILTEGDEGSETPKSDAHKVRSHTATRSRKHTMTSNSGSQHDLKLSRGNLSSDN 370

  Fly   319 RLHCPISEEQNH---------------------ESDEFLRPNNFRRERVESNLEAKLCCQCSAKR 362
            ||....:.:.|.                     :..||.||.|.:......:::
 Worm   371 RLSRVSARDFNQSLSKLSKSGGASNLSIAMSGVDPKEFQRPMNRQDIFYGGSIQ----------- 424

  Fly   363 EEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRDFTFVNLVAGLTIINFGELN 427
                 |.||.:.|...||..::.|..|: |.:.:.|:  .|:|.|.   .:.:.|..|....|
 Worm   425 -----NLKEFKEEGTMAGYRASTLSIPR-SVVGQAVS--QLNLSRT---GSRLGGPGIAEDEE-- 476

  Fly   428 FSILTPFI------------------LVDFGF--DTPQITLAMSLLAGLDITMRFMVPF-----L 467
             .::.||:                  ::|...  :...:.|.:|.|.|:   |.|.:|.     |
 Worm   477 -EMIEPFVDDGCCKVLPLPMRNALSEMIDLNLLKNKTMMILCISNLLGM---MGFYIPIMFLKDL 537

  Fly   468 TEKIPWD-NRVFFLIGVVGI--ALGRT----------VVACT-RSYSLILCSFVWIGLCKGVRTI 518
            :|.:..| :...||:.:.|:  .:||.          :.|.| .:.|||:         .|:.|:
 Worm   538 SESMKLDMSLAMFLVPIFGVFNTIGRVFFGWLTDQKILSALTINNLSLIV---------SGLLTL 593

  Fly   519 FWPL----------------IIPGYV-----------PLNRLPGASGLQLLISGLFTLIGGPFVG 556
            ..||                ||..|:           .|..|..:.||.::..|:.:|:|.||.|
 Worm   594 ACPLLTSIAGQYFYAIVFGFIISAYICLTSIVLADLMGLENLTNSFGLLVVARGIASLVGPPFAG 658

  Fly   557 LVRD---RYD 563
            :|.|   .||
 Worm   659 IVYDITGSYD 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14196	NP_573367.1	MFS_MCT_SLC16	42..585	CDD:340910	135/654 (21%)
mct-4	NP_001041267.1	MFS_MCT_SLC16	75..>252	CDD:340910	43/183 (23%)
		MFS	<507..689	CDD:475125	41/174 (24%)