Protein Alignment CG14196 and SLC16A14

DIOPT Version :10

• Sequence 1: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Sequence 2: NP_689740.2
• Gene: SLC16A14 / 151473
• HGNCID: 26417
• Length: 510
• Species: Homo sapiens
• Alignment Length: 612
• Identity: 134/612 - (21%)
• Similarity: 232/612 - (37%)
• Gaps: 149/612 - (24%)

  Fly    22 YNKHDKSDLGDDF---------VAP----DAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSD 73
            |..|:  |:|.||         :.|    |.||||::.:::...::.|.......|.|..|.|.:
Human     2 YTSHE--DIGYDFEDGPKDKKTLKPHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEE 64

  Fly    74 LGMSSSQITAIINANPAVSACTGLLNGPMFRRFT----FRQVAMAGSLLISGSLILTAFCETFLS 134
            ...|.. :||.::   ::|....|:.||....|.    .||.|:.|.|:.|...:|:|:......
Human    65 FHQSRG-LTAWVS---SLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHY 125

  Fly   135 YMVAYALLFGFGMGISVSASSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQG 199
            ..:.:.:..|.|.|::...:.:.:..||||:|..|.|.|.|.||.|...:..|:.:|...||.:.
Human   126 LFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRN 190

  Fly   200 TTLLFAAISLHSFVCALIYQPVRYHVKPPVEQLADQEQQAEALCAH------CSWQQKR---EPG 255
            ..|:..|:||:..||..:.:|    :.|........|:....|.||      .:.||.|   :.|
Human   191 AMLIQGAVSLNLCVCGALMRP----LSPGKNPNDPGEKDVRGLPAHSTESVKSTGQQGRTEEKDG 251

  Fly   256 GIFSSQYLCQDDDAQRPGYEICEPGTPMLSRANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRL 320
            |:.:.:.||                                                ||   |..
Human   252 GLGNEETLC------------------------------------------------DL---QAQ 265

  Fly   321 HCPISEEQNHESDEFLRPNNFRRERVESNLEAKLCCQCSAKREEHNNNRKEKEAEAEEAG-MESA 384
            .||  ::..|..:                    :|.....|.......|..|..|...:| ..:|
Human   266 ECP--DQAGHRKN--------------------MCALRILKTVSWLTMRVRKGFEDWYSGYFGTA 308

  Fly   385 PLHDPQMSFLAKVVTFFDLDLLRDFT--FVNLVAGLTIINFGELN--FSILTPFILVD-FGFDTP 444
            .|...:| |:|.:  |:.|.....|.  |::|...:.:.|..|.|  |.:.:...:|. ||
Human   309 SLFTNRM-FVAFI--FWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFG---- 366

  Fly   445 QITLAMSLLAGLDITMRFMVPFLTEKIPWDNRVFFLIGVVGIALGRTVVACTRSYS--LILCSFV 507
              .:.:.::|.|        |.::   .|:   .||:....:.|...::....:|:  .::|:.
Human   367 --KVILGVIADL--------PCIS---VWN---VFLLANFTLVLSIFILPLMHTYAGLAVICAL- 414

  Fly   508 WIGLCKGVRTIFWPLIIPGYVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRD---RYDYSVTLH 569
             ||...|..::. |::....|.:..|..|.|:.:..:|:..|:|.||.|.:.|   :||:|..:
Human   415 -IGFSSGYFSLM-PVVTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYI- 476

  Fly   570 C--LNMMSFVAATSWSLEALIRRHRRK 594
            |  |.|:..:.........:|.:.|||
Human   477 CGLLYMIGILFLLIQPCIRIIEQSRRK 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14196	NP_573367.1	MFS_MCT_SLC16	42..585	CDD:340910	120/568 (21%)
SLC16A14	NP_689740.2	MFS_MCT14	33..492	CDD:340987	120/566 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..255		10/40 (25%)