DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc18B and Rp1

DIOPT Version :9

Sequence 1:	NP_001285431.1	Gene:	Muc18B / 32913	FlyBaseID:	FBgn0031000	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	XP_008761780.1	Gene:	Rp1 / 681377	RGDID:	1596713	Length:	2150	Species:	Rattus norvegicus

Alignment Length:	184	Identity:	46/184 - (25%)
Similarity:	63/184 - (34%)	Gaps:	40/184 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 PSNLDESTTEKPATEAPGTTEKVTTAAPGTTEK---VTTEAP-GTTEKITTE-----------AP 142
            |.|.|......| .:.||.:.:|........||   .|...| ..|:.:.:|           ||
  Rat   257 PGNYDIQKYLLP-VKLPGISHRVHRKGKAKIEKRKMSTHSVPRPQTDSLASEKTYDCFSDFSVAP 320

  Fly   143 GTTEKITTEAPGTTEKITTEAPGTTEKITTEAPGTTE---------KPATDAPGTTEKPATDAPG 198
            .....:.|....|.....:| .|..:.|.....||..         |..| ...||.....|...
  Rat   321 ENYLALETHDSQTLSTYPSE-DGVEKSIVFNQDGTMTVVMKVRFKIKEET-VKWTTTVNRADLSN 383

  Fly   199 TTEKSETTDAPG-TTDKSDT---------DAPITDEPSTAETS-TDEPNTETTE 241
            ..|||:.:..|| |.|:|.:         ...|||  :|.:.| |:|.||:.||
  Rat   384 DDEKSKISSYPGKTEDRSSSLKLVVPCSLSEDITD--TTQQGSLTEEENTQMTE 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc18B	NP_001285431.1	CBM_14	26..72	CDD:279884
Muc18B	NP_001285431.1	MCLC	<77..177	CDD:283562	20/98 (20%)
Rp1	XP_008761780.1	DCX	60..135	CDD:176357
Rp1	XP_008761780.1	DCX	182..257	CDD:176357	46/184 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900