DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Muc18B and CG1647

DIOPT Version :9

Sequence 1:	NP_001285431.1	Gene:	Muc18B / 32913	FlyBaseID:	FBgn0031000	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_651636.1	Gene:	CG1647 / 43401	FlyBaseID:	FBgn0039602	Length:	1222	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	56/275 - (20%)
Similarity:	90/275 - (32%)	Gaps:	73/275 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 IPPSNLDESTTEKPATEAPGTTEKVTTAAPGTTEKVTTEAPGTTEKI----TTEAPGTTEKITTE 151
            :||..|...::.|........|| |:||.|      .:|.|..|..:    .:||...:..||..
  Fly   845 LPPLELQNESSRKDLESERMDTE-VSTALP------ASETPSQTRDVLGVEKSEASAFSLVITNI 902

  Fly   152 APGTTEKITTEAPGTTEKITTEAPGTTEKPATDAPGTTEKPATDAPGTTEKSETTDAPGTTDKSD 216
            ......:.:.......|.....:|.||.:|.:......:.||.|.       :|:.......:|.
  Fly   903 CSQAVPQPSAACSNDIECSIGPSPSTTNEPHSHTVENVQSPANDL-------QTSAQVAIAAQSQ 960

  Fly   217 TDAPITDEP-----STAETSTDEP--------NTETT-----ESGEETTIEDNV----------C 253
            .|..|..:|     |.|:|....|        |||:.     ...|:.:||::.          |
  Fly   961 PDPCIVSQPAASSESQADTKDLPPAASQIQTFNTESLPIHVHSETEDNSIENDASYLESRAQVDC 1025

  Fly   254 ATTGL------------FPTGSCTHFIVCSYAEGD--------------ELKAYTKKCPGEMQFD 292
            .:.|.            .|:|||...|..:.:.|:              |:.|.:..|...:..|
  Fly  1026 QSAGTENPSVVLEQNESLPSGSCVSPIPENPSPGNSPPQHDESESLDKPEMAAGSAYCLATVSLD 1090

  Fly   293 -PFNSVCSASYDCTA 306
             |.::...|...|.|
  Fly  1091 APKDTEALALPPCDA 1105

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc18B	NP_001285431.1	CBM_14	26..72	CDD:279884
Muc18B	NP_001285431.1	MCLC	<77..177	CDD:283562	19/89 (21%)
CG1647	NP_651636.1	zf-AD	19..99	CDD:285071
		C2H2 Zn finger	203..224	CDD:275368
		C2H2 Zn finger	233..253	CDD:275368
		C2H2 Zn finger	262..282	CDD:275368
		C2H2 Zn finger	297..314	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900