DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc18B and Asph

DIOPT Version :9

Sequence 1:	NP_001285431.1	Gene:	Muc18B / 32913	FlyBaseID:	FBgn0031000	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001261020.1	Gene:	Asph / 36778	FlyBaseID:	FBgn0034075	Length:	991	Species:	Drosophila melanogaster

Alignment Length:	173	Identity:	52/173 - (30%)
Similarity:	67/173 - (38%)	Gaps:	41/173 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 DDSNIENPTIPPSNLDESTTEKPATEAPGTTEKVTTAAPGTTEKVTTEAPGTTEKITTE-APGTT 145
            ||...|.|.  ...|:|...|:   |.|  ||:...||....|:...|.....|.||.| |....
  Fly   127 DDHEDEEPL--TEELEEELEEE---EEP--TEEDEPAADEEYEEDEDEENNAGENITAEDAEEEE 184

  Fly   146 EKITTEAPGTTEKITTEAPGTTEKITTEAPGTTEKPATDAPGTTEKPATDAPGTTEKSETTDAPG 210
            |:...:..||.| .|.||  ||| .||||.|..|                    .|:.:..:|..
  Fly   185 EEEDNDDEGTVE-ATVEA--TTE-ATTEATGEYE--------------------AEEDDEDEAAA 225

  Fly   211 TTDK-SDTDAPITDEPSTAETSTDEPNTETTESGEETTIEDNV 252
            ..|. ..|:||:    |.||...|:.:    |..||..||::|
  Fly   226 DDDAVESTEAPL----SKAEEQEDDED----EDEEEQEIEESV 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc18B	NP_001285431.1	CBM_14	26..72	CDD:279884
Muc18B	NP_001285431.1	MCLC	<77..177	CDD:283562	34/95 (36%)
Asph	NP_001261020.1	TPR	610..854	CDD:223533
		TPR repeat	684..714	CDD:276809
		TPR repeat	719..748	CDD:276809
		TPR repeat	757..782	CDD:276809
		Asp_Arg_Hydrox	826..977	CDD:282913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900