DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc18B and Leo1

DIOPT Version :9

Sequence 1:	NP_001285431.1	Gene:	Muc18B / 32913	FlyBaseID:	FBgn0031000	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001005548.1	Gene:	Leo1 / 300837	RGDID:	1549772	Length:	678	Species:	Rattus norvegicus

Alignment Length:	92	Identity:	20/92 - (21%)
Similarity:	38/92 - (41%)	Gaps:	17/92 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 EKITTEAPGTT--EKPATDAPGTTEKPATDAPGTTEKSETTDAPGTTDK-----SDTDAPITDEP 225
            ::::.|..|.:  |:||          |:|.....:.|:..|.|..:|:     ||.:.|...:.
  Rat   214 QQLSEEEKGNSDDERPA----------ASDNDEEKQNSDDEDRPQVSDEEKMQNSDDERPQVSDE 268

  Fly   226 STAETSTDEPNTETTESGEETTIEDNV 252
            ....:..:|...:.:||...:..||.|
  Rat   269 DRRHSDDEEEQDQKSESARGSDSEDEV 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc18B	NP_001285431.1	CBM_14	26..72	CDD:279884
Muc18B	NP_001285431.1	MCLC	<77..177	CDD:283562	1/8 (13%)
Leo1	NP_001005548.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..373		20/92 (22%)
		PHA02664	<33..183	CDD:177447
		PHA02664	<134..259	CDD:177447	11/54 (20%)
		Leo1	386..544	CDD:281933
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	559..596
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	613..678
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900