Protein Alignment Muc18B and DMP1

DIOPT Version :10

• Sequence 1: NP_573365.1
• Gene: Muc18B / 32913
• FlyBaseID: FBgn0031000
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: XP_011530007.1
• Gene: DMP1 / 1758
• HGNCID: 2932
• Length: 542
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 43/239 - (17%)
• Similarity: 106/239 - (44%)
• Gaps: 40/239 - (16%)

  Fly    26 RSSGYFALVDNTPDFYACQSTAYGGYSLRFLRCPAGLVFSSSMAQCVQSIAAFEAR---DDSN-- 85
            :.||..:...||.|        .||..|  |..|:..:|..|      .|:..:.|   ||:|
Human   269 KESGENSEQANTQD--------SGGSQL--LEHPSRKIFRKS------RISEEDDRSELDDNNTM 317

  Fly    86 --IENPTIPPSNLDESTTEKPATEAPGTTEKVTTAAPGTTEKVTTEAPGTTEKITTEAPGTTEKI 148
              :::.:...||..::...:|..::.|.:::  .:....:::.:....|.:.:.:.||..::::.
Human   318 EEVKSDSTENSNSRDTGLSQPRRDSKGDSQE--DSKENLSQEESQNVDGPSSESSQEANLSSQEN 380

  Fly   149 TTEAPGTTEKITTEAPGTTEKITT------EAPGTTEKPATDAPGTTEKPATDAPGTTEKSE--- 204
            ::|   :.|::.:|:.|.....||      |...::|:.::.....::..:.:....:|.||
Human   381 SSE---SQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLN 442

  Fly   205 -TTDAPGT--TDKSDTDAPITDEPSTAETSTDEPNTETTESGEE 245
             :.::|.:  .:.|.:...:....|:||:.::|.::|..:|..:
Human   443 FSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQ 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Muc18B	NP_573365.1	CBM_14	26..72	CDD:426342	12/45 (27%)
		motB	<90..208	CDD:183756	18/127 (14%)
DMP1	XP_011530007.1	DMP1	30..542	CDD:462128	43/239 (18%)