DRSC/TRiP Functional Genomics Resources

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Protein Alignment Muc18B and Ibsp

DIOPT Version :10

Sequence 1:NP_573365.1 Gene:Muc18B / 32913 FlyBaseID:FBgn0031000 Length:308 Species:Drosophila melanogaster
Sequence 2:NP_032344.2 Gene:Ibsp / 15891 MGIID:96389 Length:324 Species:Mus musculus


Alignment Length:169 Identity:37/169 - (21%)
Similarity:50/169 - (29%) Gaps:20/169 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    79 EARDDSNIENPTIPPSNLDESTTEKPATEAPGTTEKVTTAAPGTTEKVTTEAPGTTEKITTEAPG 143
            |..:.||.|.     :|.|....|....||..:|   .:...|.|.....|        ||....
Mouse    81 EEEETSNEEE-----NNEDSEGNEDQEAEAENST---LSTLSGVTASYGAE--------TTPQAQ 129

  Fly   144 TTEKITTEAPGTTEKITTEAPGTTEKITTEAPGTTEKPATDAPGTTEKPATDAPGTTEKSETTDA 208
            |.|....:.|.......:.||...|....|.....|:...:.....::......||:..|...|.
Mouse   130 TFELAALQLPKKAGDAESRAPKVKESDEEEEEEEEEEENENEEAEVDENELAVNGTSTNSTEVDG 194

  Fly   209 PGTTDKSDTDAPITDEPSTAETSTDEPNTETTESGEETT 247
            ...:...|..    :|....|.|..|...|.|..|.|.|
Mouse   195 GNGSSGGDNG----EEAEAEEASVTEAGAEGTTGGRELT 229

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Muc18BNP_573365.1 CBM_14 26..72 CDD:426342
motB <90..208 CDD:183756 22/117 (19%)
IbspNP_032344.2 BSP_II 17..321 CDD:461651 37/169 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 60..228 35/166 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 243..263
Integrin-binding motif. /evidence=ECO:0000250|UniProtKB:P21815 293..295
Blue background indicates that the domain is not in the aligned region.

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