DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc18B and Dmp1

DIOPT Version :9

Sequence 1:	NP_001285431.1	Gene:	Muc18B / 32913	FlyBaseID:	FBgn0031000	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001345942.1	Gene:	Dmp1 / 13406	MGIID:	94910	Length:	503	Species:	Mus musculus

Alignment Length:	149	Identity:	36/149 - (24%)
Similarity:	62/149 - (41%)	Gaps:	31/149 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 TEAPGTTEKITTEAPGTTEKITTEAPGTTEKITTEAPGTTEKPA----TDAPGTTEKPATD---- 195
            ||:..:.|:       |.:...:..|.|..:.:.|:..:.|..|    ||:..:.|:...|
Mouse    25 TESESSEER-------TGDLAGSPPPPTNSESSEESQASPEGQANSDHTDSSESGEELGYDRGQY 82

  Fly   196 -APGTTEKSETTDAPGTTDKSDT-DAPITDEPS-----------TAETSTDEPNTETTESGEETT 247
             ..|...||..|.|....|:.|: |....||.:           .::..:||.:|:||:|.|::|
Mouse    83 RPAGGLSKSTGTGADKEDDEDDSGDDTFGDEDNDLGPEEGQWGGPSKLDSDEDSTDTTQSSEDST 147

  Fly   248 IEDNVCATTGLFPTGSCTH 266
            .::|....|   |:.|..|
Mouse   148 SQENSAQDT---PSDSKDH 163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc18B	NP_001285431.1	CBM_14	26..72	CDD:279884
Muc18B	NP_001285431.1	MCLC	<77..177	CDD:283562	7/37 (19%)
Dmp1	NP_001345942.1	DMP1	1..503	CDD:311295	36/149 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..503		36/149 (24%)
		Cell attachment site. /evidence=ECO:0000255	350..352
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900