Protein Alignment Muc18B and LEO1

DIOPT Version :9

• Sequence 1: NP_001285431.1
• Gene: Muc18B / 32913
• FlyBaseID: FBgn0031000
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_001310832.1
• Gene: LEO1 / 123169
• HGNCID: 30401
• Length: 688
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 45/207 - (21%)
• Similarity: 75/207 - (36%)
• Gaps: 45/207 - (21%)

  Fly    79 EARDDSNIENPTIPPSNLDESTTEKPATEAPGTTEKVTTAAPGTTEKVTTEAPGTTEKITT--EA 141
            ||.:.|:.|:.  .||::|:.:    .:|||...|.....:.|.:..  :||.| :||..:  |.
Human    89 EASERSDHEDN--DPSDVDQHS----GSEAPNDDEDEGHRSDGGSHH--SEAEG-SEKAHSDDEK 144

  Fly   142 PGTTEKITTEAPGTTEKITT-----EAPGTTEKITTEAPGTTEKPATD----------------- 184
            .|..:|   ......|||..     .|.|:.|.....:....:...||
Human   145 WGREDK---SDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSE 206

  Fly   185 ---APGTTEKP-ATDAPGTTEKSETTDAPGTTDK-----SDTDAPITDEPSTAETSTDEPNTETT 240
               |....|:| |:|.....:.|:..:.|..:|:     ||.:.|...:.....:..:|.....:
Human   207 EEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKS 271

  Fly   241 ESGEETTIEDNV 252
            ||...:..||.|
Human   272 ESARGSDSEDEV 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Muc18B	NP_001285431.1	CBM_14	26..72	CDD:279884
		MCLC	<77..177	CDD:283562	26/104 (25%)
LEO1	NP_001310832.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..357		45/207 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	547..583

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900