Protein Alignment CG14195 and SLC16A6

DIOPT Version :10

• Sequence 1: NP_728227.1
• Gene: CG14195 / 32911
• FlyBaseID: FBgn0030998
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_024306789.2
• Gene: SLC16A6 / 9120
• HGNCID: 10927
• Length: 542
• Species: Homo sapiens
• Alignment Length: 581
• Identity: 106/581 - (18%)
• Similarity: 184/581 - (31%)
• Gaps: 207/581 - (35%)

  Fly     7 GGAGVGVAASGPVRRPTARATAGIQRRRVVKKHIQQKYMLC--------------GFAIH-AFLA 56
            |||            |...|..|..|.|:.    |.|..||              |:|:. :|..
Human     4 GGA------------PPRPAETGCSRLRMT----QNKLKLCSKANVYTEVPDGGWGWAVAVSFFF 52

  Fly    57 TPAYLYGNVVESDKDLVLRIWPAIVYQATGELCRSIMEHLDTEYSGRSRETTQYRRVFLL---AT 118
            ...:.||                 :.:..|.....:|:..:...|..|...:..  ||:|   |.
Human    53 VEVFTYG-----------------IIKTFGVFFNDLMDSFNESNSRISWIISIC--VFVLTFSAP 98

  Fly   119 LIACVS--------LMVSGILFSSAWIVVTTTTQV----VAIVFYGFFAGIG-----------SS 160
            |...:|        :|:.|:|.|:..:..:.:.:|    |||   |..:|:|           .|
Human    99 LATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAI---GIISGLGYCFSFLPTVTILS 160

  Fly   161 LYLWKTHVILEAVRPREDKYVRKTIHLCGEAFCQLFLSFVFTSLRTLYGTAQSIVLMSALLVNLI 225
            .|..|...|:.||..            .||.|.....:....:|:...|...|::.:..|.:|::
Human   161 QYFGKRRSIVTAVAS------------TGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIV 213

  Fly   226 -------------PLS--LIITKHREDA-------FTTKRISVIKAETGFAALPLRAALAANL-V 267
                         |.|  ::|.::|::|       .|...|..|.:.......|.......|| :
Human   214 IFGALLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPTHTNLEL 278

  Fly   268 ADQLDGLDTLSWRNPATTEMATPSGAVAAAVVVDTHSNYMLATDEAYV----------------- 315
            ..:.|....|...:|..:|...|        ::|    :.:..:::::
Human   279 EPKADMQQVLVKTSPRPSEKKAP--------LLD----FSILKEKSFICYALFGLFATLGFFAPS 331

  Fly   316 TYVNPNGVEI--------------------------------------MEIIPEEDETVSMMRSS 342
            .|:.|.|:.:                                      :|:|.....|||:...:
Human   332 LYIIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSLFAFT 396

  Fly   343 NATIDNYAMSASQMSHKSLSNGRLYPLTPQHPLGTGTGTGTGSSSPLPPDYANLRRIRRMSRAVT 407
            .||.....||.|..                  .|...||..|:..||..: .::..|.:||.|..
Human   397 FATEFWGLMSCSIF------------------FGFMVGTIGGTHIPLLAE-DDVVGIEKMSSAAG 442

  Fly   408 THLWWNLLDKIAMPLQQALLVPQ--LYATTLL-LSADIFSYVMCLTVL----PGLAVSHHA 461
            .:::...:..:|.|....|||.|  :|:.... .:|.:....:||.::    .||...||:
Human   443 VYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKMGLCQHHHS 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14195	NP_728227.1	None
SLC16A6	XP_024306789.2	MFS_MCT7	43..491	CDD:340980	90/512 (18%)