Protein Alignment Ulp1 and Senp2

DIOPT Version :10

• Sequence 1: NP_573362.1
• Gene: Ulp1 / 32910
• FlyBaseID: FBgn0027603
• Length: 1513
• Species: Drosophila melanogaster
• Sequence 2: XP_006522751.1
• Gene: Senp2 / 75826
• MGIID: 1923076
• Length: 593
• Species: Mus musculus
• Alignment Length: 678
• Identity: 178/678 - (26%)
• Similarity: 273/678 - (40%)
• Gaps: 181/678 - (26%)

  Fly   904 LIKYRRVDNSFPRLITNETAEDLIPNNSMAKRDQPQSSKRLSIFNPPVYTQHRVRNDAPHVPT-- 966
            |:|.||   |...|.:.....|.||    |||      .||..|      .|:|:|...:..:
Mouse    26 LLKRRR---SSSTLFSTAVDTDEIP----AKR------PRLDCF------IHQVKNSLYNAASLF 71

  Fly   967 --PFD------DEESSQRLANAGPSSRPMTYSDAVRLGHNGISESRV-------NGHSSH----- 1011
              ||.      ...:.....|..||....:.|.:..|..:|...|.:       ||.|.:
Mouse    72 GFPFQLTTKPMVSSACNGTRNVAPSGEVFSNSSSCELMSSGSCSSMLKLGNKSPNGISDYPKIRV 136

  Fly  1012 TVRREPSRLHRSILSHEMNCKDQEQYNELIRTQTNYVGSRYLKPGTPPTFQRAKAQSATSSSCSL 1076
            ||.|:..|  |.:.|.....| .|.||.              :|.     .|..::|...||.:.
Mouse   137 TVTRDQPR--RVLPSFGFTLK-SEGYNR--------------RPS-----GRRHSKSNPESSLTW 179

  Fly  1077 QDNQSNITDSFPS--------PH-----GRANPELTEYAKLINRQENEENRSPAPQQPKRNASNS 1128
            :..:..:|:....        ||     |....|..:|.||:.|.:
Mouse   180 KPQEQGVTEMISEEGGKGVRRPHCTVEEGVQKDEREKYRKLLERLK------------------- 225

  Fly  1129 SASHASTISSSASSSCSTCSTCSSSDTEPMLVKDSPEVKEANEANEANEANEANETKENDAPQPT 1193
            ..:|.||..       .|.|..||...:...:|....|:|.|..
Mouse   226 EGAHGSTFP-------PTVSHHSSQRIQMDTLKTKGWVEEQNHG--------------------- 262

  Fly  1194 TTRIKKPDFLHRRFANCIFLRNDFAENFKARANRRQLESMHLLGIAEQQANESKDERLAYEKK-- 1256
               ::...|:.::: ..:..|....   ..|:.:|         .::.:|:..|...|.:||:
Mouse   263 ---VRTTHFVPKQY-RVVETRGPLC---SMRSEKR---------YSKGKADTEKVVGLRFEKEGT 311

  Fly  1257 ---------LREVMFR-------SGAPHRPF--FEIGPLEQPEEKKETKLIPLTK-EDHARFQEM 1302
                     ..||..|       :|...|..  .||.....|.::|:.:...|.: .:|...|:|
Mouse   312 RGHQMEPDLSEEVSARLRLGSGSNGLLRRKISVLEIKEKNFPSKEKDRRTEDLFEFTEHRLIQDM 376

  Fly  1303 TTIEVTTNL-----------IFKYNLQITTDDIFTFVDGEWLNDAIINFYMSMLTERSEKRAGEL 1356
            .. |::..|           .||  |:||..||.|..:..||||.:|||||::|.|||:|:.  .
Mouse   377 EK-EISNALGHGPPDEILSSAFK--LRITRGDIQTLKNYHWLNDEVINFYMNLLVERSKKQG--Y 436

  Fly  1357 PATYAMNTFFMPRLLQAGYAGVRRWTRKVDLFSKDIIPVPVHCGNVHWCMAIIHLRNKTIFYYDS 1421
            ||.:|.:|||.|:|...||..|:|||:.|:||.::::.||:| ..|||.:.::.||.|.:.|.||
Mouse   437 PALHAFSTFFYPKLKSGGYQAVKRWTKGVNLFEQELVLVPIH-RKVHWSLVVMDLRKKCLKYLDS 500

  Fly  1422 MGRPNQPALDALVKYLHEESLDKRKQPFDM---TGFVVENAQNIPRQGNSSDCGVFSCMFAEYIT 1483
            ||:......:.|::||.:||..||....::   |.:.:: ...||:|.|.||||:|:|.:|:||:
Mouse   501 MGQKGHRICEILLQYLQDESKTKRNTDLNLLEWTHYSMK-PHEIPQQLNGSDCGMFTCKYADYIS 564

  Fly  1484 RDVPITFSQAEMLYFRTKMALEIADGKL 1511
            ||.||||:|.:|..||.||..||...:|
Mouse   565 RDKPITFTQHQMPLFRKKMVWEILHQQL 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ulp1	NP_573362.1	sbcc	<294..>551	CDD:129705
		Peptidase_C48	1331..1506	CDD:397169	78/177 (44%)
Senp2	XP_006522751.1	Peptidase_C48	<372..588	CDD:420019	91/222 (41%)