DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ulp1 and si:dkey-100n23.3

DIOPT Version :9

Sequence 1:	NP_573362.1	Gene:	Ulp1 / 32910	FlyBaseID:	FBgn0027603	Length:	1513	Species:	Drosophila melanogaster
Sequence 2:	XP_005167827.1	Gene:	si:dkey-100n23.3 / 571373	ZFINID:	ZDB-GENE-070912-345	Length:	991	Species:	Danio rerio

Alignment Length:	1058	Identity:	208/1058 - (19%)
Similarity:	326/1058 - (30%)	Gaps:	385/1058 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   719 PAEAQPGSTSEDISDPVSPEHWEQLESLDPSTICIRKTFNLIRDISESLVADPEQPEAEAHRKSI 783
            |.|.:..||..|.|: ::||....| .|.|         .:.||..::     |.|...|.|.|
Zfish     2 PDERKHNSTLSDSSN-ITPERRRAL-ILSP---------EIKRDSRQT-----ECPYKIARRGS- 49

  Fly   784 FLLRQKLADVCHKVLTEIIHGRATDEIISILREILEQT-KEIPPRPTPKRDLQEDISMGLEILKK 847
                 ...|.|  |.||:...|.::..|...:.....| .::.|:.| |:..||     |.||:|
Zfish    50 -----AAEDEC--VETEMSKDRKSNNKIHWTQLASNGTSSQLSPKST-KKSNQE-----LTILQK 101

  Fly   848 IRGMLSGWYSSRE------SETDSTDTGTGFQAQNGKGFGAGRQPENSFLSQKRRNQEENPRLIK 906
            |.         |.      .:...|:.|......:|..|    |..|...|:||.:|...|.|
Zfish   102 IH---------RNQVKVVLEDVLLTELGQSLLRCSGHTF----QKTNQSESKKRSDQTSTPTL-- 151

  Fly   907 YRRVDNSFPRLITNETAEDLIPNNSMAKRDQPQSSKRLSIFNPPVYTQHRVRNDAPHVPTPFDDE 971
                        .|:|      ..|:.||.:..|::                   |...:||.:.
Zfish   152 ------------KNKT------RTSLTKRGETNSTE-------------------PKATSPFHNN 179

  Fly   972 -ESSQRLANAGPSSRPMTYSDAVRLGHNGISESRVNGHSSHTVRREPSRLHRSILSHEMN----C 1031
             ||..:..|   ||:.:..|.  .|..|..|........:..:.:| |.:..|..|.|.|    .
Zfish   180 IESKSKSLN---SSQKLLESS--ELSSNSRSPRESESPQAALISKE-SPIQTSSSSFEENEVTLI 238

  Fly  1032 KDQEQYNELIRTQTNYVGSRYLKPGTP-PTFQRAKAQSATSSSCSLQDNQSNITDSFPSPHGRAN 1095
            :...|..|::    :.|....:...:| .|.:|.:.:.|.|   .|..|:....:|..||...|.
Zfish   239 EGSLQNEEVL----SAVCESVISSSSPVETRRRPREKKADS---ELLSNKKERRESQESPKDAAK 296

  Fly  1096 PE---LTEYAKLINRQENEENRSPAP--------QQPKRNASNSSAS----------------HA 1133
            .|   |....:|:  ||.|..|....        |.|.:.....|.|                .:
Zfish   297 HEENHLCSNGELV--QEVEGMRGSVLRLSAGTDFQIPVKRCRLDSLSEDQLLNSDLAFDTAEIRS 359

  Fly  1134 STISSSASSSCSTCSTCSSSDTE----------------PMLVKDSPEVKEANEANEANEANEAN 1182
            .|:.||..|...|....|..:.|                |...||:..|.|:....|..::.|:|
Zfish   360 FTLESSNFSQDETIVLSSEEEDEGEGREETKISALNIQPPEGTKDTNVVDESTTVYEQTKSPESN 424

  Fly  1183 -------ETKENDAPQPTTTRIKKPDFLHRRFANC----IFLRNDFAENFKARANRRQL------ 1230
                   |.:....|.|.::       ||....:.    |.:...:...|..:.|....
Zfish   425 LSITEMSEEESQGIPLPLSS-------LHMGGVSAKSSGIMMITPYKITFSLKGNSSDSTVKISL 482

  Fly  1231 -----------------------------ESMHLLGIAEQQANESKDERLAYEKKLRE------- 1259
                                         .|:..|.:::.||::..|:....|...|.
Zfish   483 SAINVYKYSLWEEHTLWGCDLDKDNEATPTSLLFLWLSDAQAHKLHDDLSVLELGTRPAESSTCL 547

  Fly  1260 ----------------------VMFRSGAPH---RPFFEIGPLEQPEEKKETKLIPL--TKEDH- 1296
                                  |:...|:|.   ....:...|...:..:||.|:.|  .|.|.
Zfish   548 LLCMAEPLSGIESALLCSLLDIVVSNQGSPELYCTCLTQSDSLNLLQSSEETHLLQLLTPKPDEQ 612

  Fly  1297 ----ARFQEM-TTIEVTTNLIFK-----YN----------------------------------L 1317
                |:.|:. ..:|.|..|..:     ||                                  |
Zfish   613 TSTSAQSQDSDVQLEPTYTLCHRRAQGSYNVFLAATPGAEWTPYKHCGPTRRLIQFPPPPSKGAL 677

  Fly  1318 QITTDDIFTFVDGEWLNDAIINFYMSMLTERSEKRAGELPATYAMNTFFMPRLLQAGYAG----- 1377
            .:||:|:.....||:|||.||:||:..|..:...:| .:..::..::||..:|.:...|.
Zfish   678 TVTTEDLECLDSGEFLNDVIIDFYLKYLLVQKAPQA-SVARSHIFSSFFYKQLTRRDNANEDSTS 741

  Fly  1378 ----------VRRWTRKVDLFSKDIIPVPVHCGNVHWCMAII----------------------- 1409
                      ||.|||.||:|.||.:.|||: ...||.:.:|
Zfish   742 TPAQVRRHQRVRTWTRHVDIFEKDFLFVPVN-QEAHWYLVVICFPGLEDPQYVKRDDSASVQGNG 805

  Fly  1410 --------------H------------------------------------LRNKTIFYYDSMGR 1424
                          |                                    |:...|...||:..
Zfish   806 GEDVGESENETQGDHRSNSDEDKSTDDSRIKSSTSLRQPDCTENTCKKDVVLKRPCILIMDSLKL 870

  Fly  1425 P-NQPALDALVKYLHEESLDKRKQPFDMTG-FVVENAQNIPRQGNSSDCGVFSCMFAEYITRDVP 1487
            . ::.....|.:||..|...||....|.:. .:|.:...:|.|.||||||::...:||
Zfish   871 SIHERIFKLLREYLQVEWETKRMGTRDFSAERMVGSHCKVPLQDNSSDCGLYLLQYAE------- 928

  Fly  1488 ITFSQAEMLYFRTKMALE 1505
             :|.|..:::|...:.||
Zfish   929 -SFLQDPVVHFDLPLRLE 945

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ulp1	NP_573362.1	Ehrlichia_rpt	200..>580	CDD:118064
Ulp1	NP_573362.1	Peptidase_C48	1331..1506	CDD:280975	58/265 (22%)
si:dkey-100n23.3	XP_005167827.1	ULP1	<678..939	CDD:227489	59/270 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810