DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ulp1 and ulp-1

DIOPT Version :9

Sequence 1:	NP_573362.1	Gene:	Ulp1 / 32910	FlyBaseID:	FBgn0027603	Length:	1513	Species:	Drosophila melanogaster
Sequence 2:	NP_498095.3	Gene:	ulp-1 / 175704	WormBaseID:	WBGene00006736	Length:	697	Species:	Caenorhabditis elegans

Alignment Length:	786	Identity:	207/786 - (26%)
Similarity:	325/786 - (41%)	Gaps:	194/786 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   807 TDEIISILREILEQTKEIPPRPTPKRDLQEDISMGL-EILKKIRGMLSGWYSSRESETDSTDTGT 870
            ||:.::     .|:.::.|.:.|.|..     |.|| .:.....||   :.||...|.:.|:...
Worm    21 TDQAVT-----NEEKEQSPTKRTRKTK-----SQGLGGLFNTFFGM---FVSSNSGEKEKTEVSG 72

  Fly   871 GFQAQNGKGF---GAGRQ-PENS----FLSQK---RRN--QEENPRLIKYRRVDNSFPRLITNET 922
            ..|.|.....   |..|: .||.    ||::.   |.|  .|||..:|: :.|..:. .:..:|.
Worm    73 EVQVQEDDEIIVEGTTRRVAENKKYMIFLNEDAPVRANAGSEENEVIIE-KHVQKNV-EIRNDEE 135

  Fly   923 AEDLIPNNSMAKRDQPQSSKRLS--------------IFNPPVYTQHR-------------VRND 960
            .:::..:..:.....|:|.|.|.              :|...|.|.::             ..||
Worm   136 KQEVQGDLVLTLSSSPKSPKNLEKSFEVQQDDEEPDVLFEKVVKTPNKQLQEARRFQNELIFLND 200

  Fly   961 APHVPTPFDD-----EESSQRLANAGPS---SRPMTYSDAVRLGHNGISESRVNGHSSHTVR--- 1014
            .|..|   ||     :..|:...:..|.   |||:|           .|.|.::.::|:.||
Worm   201 NPDTP---DDVSVISDSRSKEFISPTPDDSVSRPIT-----------PSLSSLSNYTSNNVRDYW 251

  Fly  1015 -----REPSRLHRSILSHEM-NCKDQEQYNELI--RTQTNYVGSR-YLKPGTPPTFQ-RAKAQSA 1069
                 ::|..|.|..:.|:. :.....:.|.:|  :...|::.|| .|..|...:.| .|||.|.
Worm   252 RRNSAKKPEVLRRVPVRHQFKHSTSVRKMNTIIDLKKIKNHLSSRDRLLQGVVASGQYEAKAISG 316

  Fly  1070 TSSSCSLQDNQSNITDSFPSPHGRANPELTEYA-------KLINRQ-----ENEENRSPAPQQPK 1122
            .......:..:::.||..    .||..::.|..       .|::|:     ::||:.|.:.:|..
Worm   317 IVEKKPKKMQRTSSTDIL----ARAKNKIAELGGSRSNTPSLLSREPSIIIDSEESTSSSYRQHA 377

  Fly  1123 RNASNSSASH--ASTISSSASSSCSTCSTCSSSDTEPMLVKDSPEVKEANEANEANEANEANETK 1185
            |:.|:.|.|:  .:.|.|..:|     ....|:...|...::|.::.:..|.....||
Worm   378 RSNSSESDSYRKLNDILSQINS-----LGIGSAYRGPQRYQNSYQLSKQKEDKLLEEA------- 430

  Fly  1186 ENDAPQPTTTRIKKPDFLHRRFANCIFLRNDFAENFKARANRRQLESMHLLGIAEQQANESK--D 1248
                      ||::.   ||...     |.|..|:.:.|        :.|.|||.:...|.|  |
Worm   431 ----------RIREG---HRSQT-----RGDRLEDVRKR--------LELQGIAIRPKVEKKKVD 469

  Fly  1249 ERLAY---EKKLREVMFRSGAPHRPFFEIGPLEQPEEKKETKLIPLTKEDHARFQEMTTIEVTTN 1310
            :.:|.   ...|.|..:..|.|:..|.:
Worm   470 DFMALPDAADALVERAWSGGNPNEQFVD------------------------------------- 497

  Fly  1311 LIFKYNLQITTDDIFTFVDGEWLNDAIINFYMSMLTERSEKRAGELPATYAMNTFFMPRLLQAGY 1375
               .:::||...|:.|.....||||.|||||:.::.:||...: :.|..||.||||...::..||
Worm   498 ---AFSIQICKKDLATLSGLHWLNDEIINFYLQLICDRSNGDS-KYPKIYAFNTFFYSNIVSKGY 558

  Fly  1376 AGVRRWTRKVDLFSKDIIPVPVHCGNVHWCMAIIHLRNKTIFYYDSMGRPNQPALDALVKYLHEE 1440
            |.|:|||||||:|:.||:.||||.| :|||||:|.:..|.|.:|||:...|...|.||..||..|
Worm   559 ASVKRWTRKVDIFAFDIVLVPVHLG-MHWCMAVIDMGEKKIEFYDSLYDGNTAVLPALRGYLEAE 622

  Fly  1441 SLDKRKQPFDMTGFVVENAQNIPRQGNSSDCGVFSCMFAEYITRDVPITFSQAEMLYFRTKMALE 1505
            ||||:|...:.:|:.::...:||||.|.||||||||.|.|:.:|.....|:|..|.|:|.:|..|
Worm   623 SLDKKKTAMNFSGWTIQQMTDIPRQQNGSDCGVFSCQFGEWASRRTTPRFTQKNMPYYRKRMVYE 687

  Fly  1506 IADGKL 1511
            |...||
Worm   688 IVSKKL 693

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ulp1	NP_573362.1	Ehrlichia_rpt	200..>580	CDD:118064
Ulp1	NP_573362.1	Peptidase_C48	1331..1506	CDD:280975	83/174 (48%)
ulp-1	NP_498095.3	Peptidase_C48	<425..692	CDD:304959	112/341 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167915
Domainoid	1	1.000	175	1.000	Domainoid score	I2177
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2988
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000698
OrthoInspector	1	1.000	-	-		otm14776
orthoMCL	1	0.900	-	-		OOG6_101235
Panther	1	1.100	-	-	O	PTHR12606
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.650