Protein Alignment Ulp1 and velo

DIOPT Version :10

• Sequence 1: NP_573362.1
• Gene: Ulp1 / 32910
• FlyBaseID: FBgn0027603
• Length: 1513
• Species: Drosophila melanogaster
• Sequence 2: XP_061498492.1
• Gene: velo / 1276547
• VectorBaseID: AGAMI1_011776
• Length: 2049
• Species: Anopheles gambiae
• Alignment Length: 1924
• Identity: 357/1924 - (18%)
• Similarity: 581/1924 - (30%)
• Gaps: 755/1924 - (39%)

  Fly   207 YYVQQYNNQPVLYQQNIHIGTGIQLC--DQASENNQPIILHIVEHNP-QTITESQEQFHQVVPEI 268
            |.:.|.:.....||| |:|..||||.  |.....:|.:||...:.|. |.|....:..||:..:.
Mosquito     5 YEIVQQDELKNAYQQ-INIDNGIQLVMGDDVQFGSQQVILSQEQPNEVQLIGGVYQTAHQIPQQQ 68

  Fly   269 QINNIQEQDQKFENGISEQNH----------------PIAT-EAQDQTLTEIRDENQIVLAVQEK 316
            |    |:|....:..|.:.|:                |:|| :.|.|...:.:.:.|..|..|::
Mosquito    69 Q----QQQQHHQQQHIQDANYLGQANTSMVADTYMQSPMATQQTQLQHQQQQQQQQQPPLQQQQQ 129

  Fly   317 --------------NLTRASEIQDQN-----QQTLTEIPEKCLQIASPVTTDIQVQSPQVVI--- 359
                          .|.:||.|..|.     ||||     ..:|.||    :.|:..||..|
Mosquito   130 QQQQQIYYTDESTGQLVQASNILPQEPLLDPQQTL-----HVMQTAS----EQQLHQPQQQILHQ 185

  Fly   360 --------EIQEQNHQSVTEIQEEVHQTAPEIQVNVFQTSSDIQG-QNHQIVTEEQNHQTITETQ 415
                    :.|:|.|||..:.|:..|.  |.:||        :|| |.|     .|.|..|.:|.
Mosquito   186 QLTPPPQQQQQQQQHQSPVQQQQITHH--PVVQV--------VQGIQRH-----GQQHIIIRQTD 235

  Fly   416 EDYSAVSEIQWENLSFSAEIQEQNQQIVTEVTKLASPSVTDIQAQSPQSVIEIQDDDDEDLKFES 480
            :..|....:|          |.|.|.|:|.    ..|:...:|:|....:|:.|....:.
Mosquito   236 QSKSLQGGLQ----------QTQQQHILTH----QQPTQVILQSQGTSQLIQRQQQQQQQ----- 281

  Fly   481 DDLHTIPEIQEKNQQS-PQFVIEIHYDNEDLKFASDNQEQDQQTAELQKERFQFASEIEKRDLQI 544
                  |:.|::..|| .|.:|   ||...|:.....|:|.||...|..........::::..|.
Mosquito   282 ------PQQQQQTDQSNAQHII---YDQISLQSQQQPQQQQQQIVSLSTIHQTGGGPVQQQQQQQ 337

  Fly   545 VTDTHKQNYHN---------VTDIPF----------------ATYIQEENEQLTPEDQEED---Q 581
            .....:|..|:         :|.|..                .|...::::||.|:.|...   :
Mosquito   338 SQQQQQQQQHHQQPKPSQPQITQIQLQQLPQQQQQRVFSKGALTLTAQQHQQLFPQQQLHQGAPR 402

  Fly   582 H--YLNFEGNQQFQLQKQDQLSVPQIQKQTHQFESKVKKRKLQPFSEYQQKGQKDHIQERQYIQQ 644
            |  .|...||||.....|..|:..|.|:|..|.:|.|.::.....::.||..|:.  |::|.::|
Mosquito   403 HCILLTKTGNQQHIGGTQIVLNQQQQQQQPIQMQSNVVQQSAMLTTQQQQPVQQQ--QQQQALKQ 465

  Fly   645 EFTIHSNQAYSKVQYIQTIQT------------------------ATPYVPQLEISQENSFEVQ- 684
            :......|..:.|..:|..|:                        |.|..|:..::..|:.:::
Mosquito   466 DGQQQQQQTQTTVAAVQLAQSAVPKGGAADTLLRPRLTRPRGAKPAAPRQPRSNMATVNAVQMRG 530

  Fly   685 ----------------PAY--------EVNEGQRDRELVSYTGHEHQN-FVDEVSTPL------- 717
                            ||.        .||..|..::...|.|...:| .|......|
Mosquito   531 PRPPTTTQIITTQIRAPAQVATSVSGGTVNAQQSAQQTAVYQGITARNVMVGNTRAKLLTINRTP 595

  Fly   718 -----------PPA-----EAQPGSTSEDISDPVS--PEHWEQLESLDPSTICIRKTFNLIRDIS 764
                       ||.     ...||.||...|.|:|  .:..:|.:.:.|..:.:
Mosquito   596 QAGGLATYQNPPPRLTVMHRTNPGPTSGQTSIPISQQQQQQQQQQQMQPQLLQV----------- 649

  Fly   765 ESLVADPEQP-EAEAHRKSIFLLRQKLADVCHKVLTEIIH----GR-----------ATDEIISI 813
             ||.:..:|| .|.....:........|.......|.::|    |:           ||.|..|
Mosquito   650 -SLASIVQQPNSATGSPVTTVSTATGTAPATGGTATAVVHPYNVGKPAVVVKTEPEAATSETGS- 712

  Fly   814 LREILEQTKEIPPRPTPKRDLQEDI-SMGLEILKKIRGMLSGWYS---------SRESETDSTDT 868
             .|:::....|.....|:|...::: |.|...| .|.|.....|:         .::.:..:|..
Mosquito   713 -GEMIDLEDSIKAAVLPRRAGTDEVGSSGTGTL-SIAGTSGPIYTIHTQQPTMQHQQQQRVATTN 775

  Fly   869 GTGF---------QAQNGK------------------------GF---GAGRQPENSFLSQKR-- 895
            |..|         ...||:                        ||   |.||.|:...:.::|
Mosquito   776 GLSFVTNDPNSLIHLANGQTVTSAQFRTFQEKQQQRQQEAFRGGFSQQGRGRAPQRGMMIRQRGG 840

  Fly   896 ---------RNQEENPRLIKYRRVDNSFPRLITNETAEDLIPNNSMAKRDQPQSSKRLSIFN--- 948
                     :..:..|.::.......:.|:...:.:|..::.|..|.   ||.:..:|....
Mosquito   841 AVGRQMVAIQTPQAQPTMMATSAPQITLPQGPIHISAAQVLQNQGMV---QPATQLQLQTGTLQQ 902

  Fly   949 -PPVYTQHRVRNDAPHV-PTPFDD--------EESSQRL-------------------------- 977
             .|..|..:|:...|.. .|.|.:        :...|||
Mosquito   903 VTPTTTLRQVQTIGPQTGETEFRESARMLVILQSGEQRLITFTLPKESCTVQDLLEQVQVQYSPD 967

  Fly   978 ANAGPSSRP---MTYSDAVRLGHNGI------------SESRVNGHSSHT--------------- 1012
            :|....|.|   :.|...|.:|.:..            |:.::|.||..:
Mosquito   968 SNIQCISNPGGDVDYIVTVGIGESETAEVIRQAEITLRSQFQLNNHSHQSQPMLQQQQQQQQQQQ 1032

  Fly  1013 -----VRREPSRLHRSILSHEMNCKDQEQYNELI--------------------------RTQTN 1046
                 .:::..:..:.:...:...:.|:|..:.:                          :.|..
Mosquito  1033 QQQQQQQQQQQQQQQQLQQQQQQQQQQQQQQQTMIPQACVIQQPQTMMITLQSQQPQQQQQQQQQ 1097

  Fly  1047 YVGSRY-------LKPGTPPTFQRAKAQSATSSSCSLQDNQSNITDSFPSPHGRANPELTEYAKL 1104
            :|.||:       :..|||.:.       ||||...    ||.:..:.|.   .|.||:.:  ||
Mosquito  1098 HVISRFADSYRQTISLGTPVSI-------ATSSGTM----QSLLQTTTPE---TAGPEVKQ--KL 1146

  Fly  1105 I-----------------------NRQENEE-NRSPAPQQPKRNASNSSASHASTISSSASSS-- 1143
            |                       .|...|. .|.|.|.:....|.....||...:.:|...|
Mosquito  1147 IKGFLAVCASCGYTGLDHAKCQRCKRIFTESPRRIPEPDKTPGAALTPGGSHPPPLVTSTPMSGP 1211

  Fly  1144 ------------------------------------CSTCS----------TCSSSDTEPMLVKD 1162
                                                .|..:          |.||.|.|....:.
Mosquito  1212 VRNKYDIYAKKQAMNTILLRSGRGGSARSGRGRGGRASVATKYPDVDPPVFTLSSDDEETSTSER 1276

  Fly  1163 S-----PEVKEANEANEANEA------------NEANETK-ENDAPQPTTTRIKK-PDFLHRRFA 1208
            |     ..|..:::||.::::            |||:.:. .||.|:...|.:|. ||....:.
Mosquito  1277 SKTLYKTAVNSSSKANASSQSIKRDPLPCEPTNNEADTSAVVNDKPRLDITDVKNLPDGQITQI- 1340

  Fly  1209 NCIFLRNDFAENFKARAN-----------------RRQLESMHLLGIAEQQANESKDERLAYEKK 1256
            :|..:|   ....|..||                 :|..|.:.|    :.|.||.|.....:.|.
Mosquito  1341 DCSTIR---VGTLKYEANEKVTISSKGVRIVAPNVKRPTEFVSL----DLQMNEMKKVLTHFSKG 1398

  Fly  1257 LREVM----FRSGAPHRPFFEIGPLE------QPE------EKKETKLIPLTKED---------H 1296
            |..:.    ...||..|...|:.|..      :||      .|:...|:....|:         |
Mosquito  1399 LNVIFLYTNISGGAYVRKHLEMDPSSDKLPCFRPEIASNDLTKRIILLVDSISEEAKSIIKNIFH 1463

  Fly  1297 ARFQEMTTI----------------------------------------EVTTNLIF---KYNLQ 1318
            ....|..:|                                        |:.|.||:   ...:.
Mosquito  1464 PDLLEEISIRDAKELILRCSSSRSSYTSSAANALVDANGSGSNDTNDSLEIRTILIYPPGPGGIT 1528

  Fly  1319 ITTDDIFTFVDGEWLNDAIINFYMS-----MLTERSEKRAGELPATYAMNTFFMPRL-------- 1370
            |.|:|.......::|||.||:||::     ||.:      ||..:.:..:|||..||
Mosquito  1529 INTEDYLCLAKDQYLNDIIIDFYLNYLKLEMLDD------GERQSVHIFSTFFYNRLTTLTTRQR 1587

  Fly  1371 -------------LQAGYAGVRRWTRKVDLFSKDIIPVPVHCGNVHWCMAI-------------- 1408
                         .|..:|.|..||:|.::|.|..|.:|:: ...||.:||
Mosquito  1588 GPPGDRGDVRLSAAQKRHARVANWTKKDNIFDKKFIVIPIN-EQSHWFLAIICFPGLDCPVTASN 1651

  Fly  1409 --------------------------------------------IHLRNKTIFYYDSM------- 1422
                                                        |||.:..:...|..
Mosquito  1652 NTPAPSVSTVAKPKPKSAPRSKRNLTMQIGSTTITPVSKREIESIHLADDDMCERDEADGDESEL 1716

  Fly  1423 --------------GRP--NQPAL-------------------DALVKYLHEESLDKRKQPF--- 1449
                          |||  .||.:                   |.|......:..||..:.|
Mosquito  1717 ATDAEDSDDEPSDDGRPPIKQPCILIFDSLTGASRSRVVATLRDYLTCEYRVKMPDKPAKQFNKL 1781

  Fly  1450 DMTGFVVENAQNIPRQGNSSDCGVFSCMFAEYITRDVPI 1488
            :|.|..|:    :|:|.|.:|||::...:.|:...| ||
Mosquito  1782 NMPGHCVK----VPQQNNYTDCGLYLLQYVEHFFLD-PI 1815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ulp1	NP_573362.1	sbcc	<294..>551	CDD:129705	66/288 (23%)
		Peptidase_C48	1331..1506	CDD:397169	57/287 (20%)
velo	XP_061498492.1	None