DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ulp1 and Senp5

DIOPT Version :9

Sequence 1:	NP_573362.1	Gene:	Ulp1 / 32910	FlyBaseID:	FBgn0027603	Length:	1513	Species:	Drosophila melanogaster
Sequence 2:	XP_006248537.1	Gene:	Senp5 / 103689978	RGDID:	1304604	Length:	750	Species:	Rattus norvegicus

Alignment Length:	857	Identity:	175/857 - (20%)
Similarity:	302/857 - (35%)	Gaps:	235/857 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   748 PSTICIRKTFNLIRDISESLVADPEQPEAEAHRKSIFLLRQKLADV--CHKVLTEIIHGRATDEI 810
            |..:|..|.     .:...:|...:....:.:::.:.:.:....||  |.|..:    |.||..:
  Rat    34 PQNLCFLKA-----KLGRPVVWHRQSKHFQCNKRGLHIQKTWTQDVPLCSKTKS----GVATQNV 89

  Fly   811 ISILREI-LEQTKEIPPRPTPKRDLQED------ISMGLE------ILKKIRGM----LSGWYSS 858
            .|:..:: .:.||...........||.|      .::|.|      :||.:.|:    :.|..:.
  Rat    90 SSLYAKVKRKDTKHFISSSRSLLKLQADKLLSSAKNLGREYCREKSLLKAVTGLSANTVLGKANG 154

  Fly   859 RESETD--STDTGTGFQAQNGKGFGAGR---------------------------------QPEN 888
            .:..||  ::|....|..::.....:|:                                 ||..
  Rat   155 HKPSTDPQASDFPMKFNGESQSPSDSGKTVVLNKHRKRVCYGCYQGLEHHRNRRPLIPKKFQPNQ 219

  Fly   889 S----------------------FLSQKRRNQEENPRLIKYRRVDNSFPRLITNETAEDLIPNN- 930
            .                      |.||..|.:.   |:.|.|:...|:.:.:|.:..|:...||
  Rat   220 HRRVKVSLMMYEKLSMIRFRYRIFRSQHFRTKS---RVCKLRKAQRSWVQKVTGDHQENFRDNNT 281

  Fly   931 -----SMAKRDQPQSSKRLSIFNPPVYTQHRVRNDAPHVP------TPFDDEESSQRLANAGPSS 984
                 |.....:|:...|...:.|.:.:...|:....|||      :|..|:|..  |..|.|..
  Rat   282 EGGDCSPVPSLEPKDPCRCQPYFPDMDSSAVVKGKNCHVPDGHTKESPALDKEHG--LDAAFPDQ 344

  Fly   985 RPMTYSDAVRLGHNGISESRVNGHSSHTVRREPSRLHRSILSHEMNCKDQEQYNELIRTQTNYVG 1049
            :                    ||.:::|..:..|       |.:..|  .||.:|:  ....:..
  Rat   345 Q--------------------NGSTTYTWDQPSS-------SPKWEC--TEQIHEI--PLMGHPS 378

  Fly  1050 SRYLKPGTPPTFQRAKAQSATS--SSCSLQDNQSNITDSFPSPHGRANPELTEYAKLINRQENEE 1112
            |....|||.........:|.||  |...::.:.|...:|..|..|
  Rat   379 SDNFTPGTERALMTLGQESGTSAVSDDGVKLSVSGADESVSSVDG-------------------- 423

  Fly  1113 NRSPAPQQPKRNASNSSASHASTISSSASSSCSTCSTCSSSDTEPMLVKDSPEVKEANEANEANE 1177
               |..::|.:|.:.......|...:..||.......|.|    |:   |:|.|     .:|...
  Rat   424 ---PVSEEPAQNENFQMEEDGSLRQNILSSKLLDHPYCKS----PL---DAPLV-----CSELKV 473

  Fly  1178 ANEANETKENDAPQPTTTRIKKPDFLHRRFANCI--FLRNDFAENFKARANRRQLESMHLLGIAE 1240
            .|:....|......|..         ..:.:.|:  ||    .|..|...:...|....:||
  Rat   474 ENQVAGGKSGQTASPVD---------DEQLSTCLSGFL----DEVMKKYGSLVPLSEKDVLG--- 522

  Fly  1241 QQANESKDERLAYEKKLREVMFRSGAPHRPFFEIGPLEQPEEKKETKLIPLTKEDHARFQEMTTI 1305
                           :|::|.....:..:||.         .::.|..       .||.|:
  Rat   523 ---------------RLKDVFNEDFSNRKPFI---------NREITNY-------RARHQK---- 552

  Fly  1306 EVTTNLIFKYNLQITTDDIFTFVDGE-WLNDAIINFYMSMLTERSEKRAGELPATYAMNTFFMPR 1369
               .|....||..:...|....:||: ||||.:||.|..::.:....:      .:..|:||..:
  Rat   553 ---CNFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVPDK------VHFFNSFFHRQ 608

  Fly  1370 LLQAGYAGVRRWTRKVDLFSKDIIPVPVHCGNVHWCMAIIHLRNKTIFYYDSMGRPNQPALDALV 1434
            |:..||.||:|||:|||||.|.::.:|:|. .|||.:..:.|.::.|.:|||.|...:..::.:.
  Rat   609 LVTKGYNGVKRWTKKVDLFKKSLLLIPIHL-EVHWSLITVTLSSRIISFYDSQGIHFKFCVENIR 672

  Fly  1435 KYLHEESLDKRKQPFDMTGFVVENAQNIPRQGNSSDCGVFSCMFAEYITRDVPITFSQAEMLYFR 1499
            |||..|:.:|.:..| :.|:.....:.||:|.|.||||||...:.:.:..:.|..|||.:|...|
  Rat   673 KYLLTEAREKNRPEF-LQGWQTAVTKCIPQQKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPRVR 736

  Fly  1500 TKMALEIADGKL 1511
            .::..|:.:.:|
  Rat   737 KRIYKELCECRL 748

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ulp1	NP_573362.1	Ehrlichia_rpt	200..>580	CDD:118064
Ulp1	NP_573362.1	Peptidase_C48	1331..1506	CDD:280975	58/175 (33%)
Senp5	XP_006248537.1	DEK_C	489..546	CDD:400903	13/96 (14%)
Senp5	XP_006248537.1	Peptidase_C48	576..748	CDD:397169	59/179 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339712
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1480705at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12606
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.850