DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ulp1 and senp1

DIOPT Version :9

Sequence 1:	NP_573362.1	Gene:	Ulp1 / 32910	FlyBaseID:	FBgn0027603	Length:	1513	Species:	Drosophila melanogaster
Sequence 2:	XP_002933743.1	Gene:	senp1 / 100485161	XenbaseID:	XB-GENE-1014921	Length:	621	Species:	Xenopus tropicalis

Alignment Length:	586	Identity:	184/586 - (31%)
Similarity:	265/586 - (45%)	Gaps:	152/586 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  1036 QYNELIRTQTNYVGSRYL--------KPGTP-PTFQRAKAQSATSSSCSLQDNQ---SNITDSFP 1088
            |.:|||:.:.|..|...|        ||..| .:...|:..|...::.|::.|.   |....|||
Frog    77 QSSELIKGKQNGNGYAMLPAKGIFFQKPRVPRSSHMEARKPSGALNAVSVKPNHTVTSAYEKSFP 141

  Fly  1089 ----------------SPH--GRANPELTEYAKLINRQENE-----------------ENRSPAP 1118
                            ||.  .|..|...|  :.:..:|.|                 ::.|..|
Frog   142 FKNISCSASLAGPCRRSPKKIQRRLPSTVE--ETVREEEKEIYRQLLQVVTGKSFLATKSTSVLP 204

  Fly  1119 QQPKRNASNSSASH---ASTISSSASSSCSTCSTC---------SSSDTEPMLVKDSPEVKEANE 1171
            .|..|.:|::|...   ||::||...||..|.|:|         |...:||:| .:|...|..::
Frog   205 PQVSRLSSDNSICGQPIASSLSSLEPSSLDTESSCRTSFSYLQPSGQISEPLL-SNSTNYKVTSD 268

  Fly  1172 ANEANEANEANETKENDAPQPTTTR------------IKKPD----------FLHRRF----ANC 1210
            ...|     :|:....:...||:.:            :.||.          |.|...    ...
Frog   269 TQGA-----SNQQLPKEKFVPTSQQSQGSDSVIVLDPVVKPQVPGQVPTSQPFFHAELWIKELTS 328

  Fly  1211 IFLRNDFAENFKARANRRQLESMHLLGIAEQQANESKDERLAYEKKLREVMFRSGAP-HRPFFEI 1274
            :|       :.:||..|||:|        ||:|...|.::    ::|:|...:.... |
Frog   329 LF-------DSRARERRRQIE--------EQKAVALKLQK----QRLQECSVQDSIDLH------ 368

  Fly  1275 GPLEQPEEKKETKLIPLT----KEDHA------RFQEMTTI---EV---------TTNLIFKYNL 1317
              |..|.||:    ||:|    :||.:      .|.|:|..   |:         ...|...|.|
Frog   369 --LRVPLEKE----IPVTLIQKQEDESTQSEEIEFPELTEAMEREIKRALFGGSQDQTLSEGYRL 427

  Fly  1318 QITTDDIFTFVDGEWLNDAIINFYMSMLTERSEKRAGELPATYAMNTFFMPRLLQAGYAGVRRWT 1382
            .||..||.|.....||||.||||||:::.||| ||.| ||..:|.||||..:|..|||..|:|||
Frog   428 TITRKDIMTLHSLNWLNDEIINFYMNLIMERS-KRKG-LPKVHAFNTFFFTKLKSAGYQAVKRWT 490

  Fly  1383 RKVDLFSKDIIPVPVHCGNVHWCMAIIHLRNKTIFYYDSMGRPNQPALDALVKYLHEESLDKRKQ 1447
            :|||:||.:|:.||:|.| ||||:|::..|.|:|.|:||||..|..|...|::||.:||:||:..
Frog   491 KKVDIFSMNILLVPIHLG-VHWCLAVVDFRKKSILYFDSMGGLNNEACKILLQYLKQESIDKKGV 554

  Fly  1448 PFDMTGFVV--ENAQNIPRQGNSSDCGVFSCMFAEYITRDVPITFSQAEMLYFRTKMALEIADGK 1510
            .||..|:.:  :.::.||:|.|.||||:|:|.:|:|||:|..|||:|..|.|||.||..||...|
Frog   555 SFDSNGWTLTSKTSEEIPQQMNGSDCGMFACKYADYITKDKSITFTQRHMPYFRKKMVWEILHQK 619

  Fly  1511 L 1511
            |
Frog   620 L 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ulp1	NP_573362.1	Ehrlichia_rpt	200..>580	CDD:118064
Ulp1	NP_573362.1	Peptidase_C48	1331..1506	CDD:280975	91/176 (52%)
senp1	XP_002933743.1	ULP1	<382..621	CDD:227489	109/242 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	188	1.000	Domainoid score	I3252
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1480705at2759
OrthoFinder	1	1.000	-	-		FOG0000698
OrthoInspector	1	1.000	-	-		otm47751
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010