DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ulp1 and senp6

DIOPT Version :9

Sequence 1:	NP_573362.1	Gene:	Ulp1 / 32910	FlyBaseID:	FBgn0027603	Length:	1513	Species:	Drosophila melanogaster
Sequence 2:	XP_031757351.1	Gene:	senp6 / 100135175	XenbaseID:	XB-GENE-962887	Length:	1193	Species:	Xenopus tropicalis

Alignment Length:	827	Identity:	172/827 - (20%)
Similarity:	262/827 - (31%)	Gaps:	297/827 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   854 GWYSSRESETD-------------STD--------------TGTG------------------FQ 873
            |:|:|.:||.|             |.|              |||.                  .:
Frog   103 GFYNSEDSEDDTEKDEANLLSLDESDDVDLQITEQKPKHHRTGTARALGETIRTYERRGRTLHLR 167

  Fly   874 AQNGKGFGAGRQPENSFLSQKRRNQEENPRLIKYRRVDN--SFPRLITNETAEDLIPNNSMAKRD 936
            |..|...|......:..|.:..:|...:...:.:.|:.:  :.||......|:      |:.|||
Frog   168 ALKGNAIGLNMLGTSKKLGENAQNIPVSSGTMVHGRIFHHANIPRSTVKTAAQ------SLEKRD 226

  Fly   937 QPQSSKRLSIFNPPVYTQHRVRNDAPHVPTPFDDEESSQRLANAG-PSSRPMTYSDAV-RLGHNG 999
            :.:.         |.:.| :|.:|...|.|....|...:|..... .||.|......| :...:.
Frog   227 RKEY---------PAHVQ-KVESDPGRVHTSPRSENMQERKEEPDFESSEPEKIKRKVQQRRRSS 281

  Fly  1000 ISESRVNGHSSHT-----------------------VRREPSRLHRSILSHEMNCKDQEQYNE-- 1039
            |.||.::  .|||                       |:.......:||...:..||.....||
Frog   282 IQESDIS--LSHTPQMCLTHQELMRQTEDLQFCALCVKENKKTKCQSIGGSQRLCKQPIALNELS 344

  Fly  1040 -LIRTQTNYVGSRYLKPG-TPPTFQRAKAQSATSSSCSLQDNQSNITDSF---PSPHGRANPE-- 1097
             |.|...:.:..|....| ...||.|        |||    ||...:|:|   .||..:..|.
Frog   345 PLSRPSIHQIDGRTANLGFKVKTFYR--------SSC----NQQTPSDTFLEHESPRFQQCPANG 397

  Fly  1098 ---LTEYAKLINRQENEENRSPAPQQP----------KRNASNSSASHASTIS-SSASSSCSTCS 1148
               |.....:....:|...||..|.:|          :.|||..|.:...:|| ..|.|:||  |
Frog   398 KFGLANEGNISKATKNMRLRSTGPSEPNDPIVLSSDDEDNASTGSTNRIESISPRPADSACS--S 460

  Fly  1149 TCSSSDTEPMLVKDSPEVKEANEANEANEANEANET--------KENDAPQPTTTRIKK------ 1199
            ...||......:|::..:.|....|...:|  ||.|        |:......|:|.:|:
Frog   461 PAPSSGKVEAALKENSFILEQKFCNSNTDA--ANTTALPRKAKMKDQFGNAVTSTPVKRRKVLTL 523

  Fly  1200 ---PDFLHRRFANCIFL----RNDFAENFKARANRRQLESMHLLGIAEQQANE------------ 1245
               ||.....:.||..|    |:....:|...|....:.||..:.|..:...|
Frog   524 ETPPDPALEPYPNCESLILNCRSVRIGSFYREAIEHVVLSMDFIAIKWEVLPENGGSQELVLKTS 588

  Fly  1246 --SKDERLAYEKKLREVMFRS----------------------------------------GAP- 1267
              :|.|..|. :||..|.|::                                        .||
Frog   589 ELTKSEWCAV-RKLPVVFFQTVPAACQSLRSHLKLSRENGTGWYDCRAANLEEQFIVLIFENAPD 652

  Fly  1268 -------HRPFFEIGP--------LEQPEEKKETKLIPLTK--ED-------------------- 1295
                   .:..:.||.        ::.|.|....:|:..||  ||
Frog   653 MQATAVLEKILYTIGKKNGMPNFFIKIPFEDANGRLVAFTKSSEDIPMLGSTQKENLKKNVGTET 717

  Fly  1296 ------HARFQEMTTIEVTTNLIF---------------KYNLQITTDDIFTFVDGEWLNDAIIN 1339
                  .::.|.....|..|:.:|               |..:.:|.:|:....:||:|||.||:
Frog   718 RMKLRNSSQLQFFGDDEGDTHTVFVGPVEKLFVYPPPPAKGGISVTNEDLHCLNEGEFLNDVIID 782

  Fly  1340 FYMSMLT-ERSEKRAGELPATYAMNTFFMPR----------------LLQAGYAGVRRWTRKVDL 1387
            ||:..|. |:..|.|..:   :..::||..|                |.|..:..|:.|||.||:
Frog   783 FYLKYLVLEKLRKDADRI---HIFSSFFYKRLNQRERRNLQDTANLTLQQRRHGRVKTWTRHVDI 844

  Fly  1388 FSKDIIPVPVHCGNVHWCMAII---------HLRNKTIFYYDSMGRP 1425
            |.||.|.||:: ...||.:|:|         |..|.   ||..:..|
Frog   845 FQKDFIFVPLN-EAAHWFLAVICFPGLEKPEHYPNP---YYQEVSSP 887

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ulp1	NP_573362.1	Ehrlichia_rpt	200..>580	CDD:118064
Ulp1	NP_573362.1	Peptidase_C48	1331..1506	CDD:280975	38/121 (31%)
senp6	XP_031757351.1	ULP1	<757..868	CDD:227489	37/114 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910