Protein Alignment CG14194 and TMEM185B

DIOPT Version :9

• Sequence 1: NP_573360.1
• Gene: CG14194 / 32908
• FlyBaseID: FBgn0030996
• Length: 358
• Species: Drosophila melanogaster
• Sequence 2: NP_077026.2
• Gene: TMEM185B / 79134
• HGNCID: 18896
• Length: 350
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 164/362 - (45%)
• Similarity: 230/362 - (63%)
• Gaps: 16/362 - (4%)

  Fly     1 MNLESLFRDFNPCKFIVHCSLFIFVTLFALRLDNYIDWPYWAIFTPLWIWKCTAILGAIVGAIVW 65
            ||...||:||||.||:::..|.:|..|..||||..|.|.|||:|.|:|:||...:.||.|||.||
Human     1 MNPRGLFQDFNPSKFLIYTCLLLFSVLLPLRLDGIIQWSYWAVFAPIWLWKLLVVAGASVGAGVW 65

  Fly    66 CRYPHYRLEGDAYTQFKAMLISLALHLILLMFELLACDKLTSDRHLWVLVFIPLIFGSVVSVGAC 130
            .|.|.||.||:|..:||||||::.:||:|||||:|.||::....|.|:|||:||.|.|.|||.||
Human    66 ARNPRYRTEGEACVEFKAMLIAVGIHLLLLMFEVLVCDRVERGTHFWLLVFMPLFFVSPVSVAAC 130

  Fly   131 VWAVKHDRSFELELFLAVNALQFVSLPLKLDRFVYWNWDVVFVPMWIVICLSLVSVLYNIIFCGI 195
            ||..:||||.|||:..:||.|||:.:.|||||.::|.|.|||||:||::....:.|||.|::..:
Human   131 VWGFRHDRSLELEILCSVNILQFIFIALKLDRIIHWPWLVVFVPLWILMSFLCLVVLYYIVWSLL 195

  Fly   196 MMRTPEVSLQQKKAALNAAVGNICTVLPLLCFQVVICDKLDGELKFPYIVVFSPLLVSILALIVL 260
            .:|:.:|..:|::..:..|:..|..|:|||.|:|::..:|||...|.|:.:|.||.:|:|.|:..
Human   196 FLRSLDVVAEQRRTHVTMAISWITIVVPLLTFEVLLVHRLDGHNTFSYVSIFVPLWLSLLTLMAT 260

  Fly   261 SSSAKGGNMWWFGIRKSFSQFLLSAMPFLQEYGNISY--HPETHSNAAQSMPLDAASSSTSMAAS 323
            :...||||.||||||:.|.||||...|||:|||||||  |.|...:|.:          ||:..:
Human   261 TFRRKGGNHWWFGIRRDFCQFLLEIFPFLREYGNISYDLHHEDSEDAEE----------TSVPEA 315

  Fly   324 EQLHEFHKHDKKSKKGAKNDILK--PVVPFVSIDLPD 358
            .::...  ..||::........|  |..|.::||:||
Human   316 PKIAPI--FGKKARVVITQSPGKYVPPPPKLNIDMPD 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14194	NP_573360.1	Tmemb_185A	30..253	CDD:287271	109/222 (49%)
TMEM185B	NP_077026.2	Tmemb_185A	31..253	CDD:370938	108/221 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152398
Domainoid	1	1.000	243	1.000	Domainoid score	I2219
eggNOG	1	0.900	-	-		E1_KOG3879
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15760
Inparanoid	1	1.050	332	1.000	Inparanoid score	I2433
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48330
OrthoDB	1	1.010	-	-		D529772at33208
OrthoFinder	1	1.000	-	-		FOG0005810
OrthoInspector	1	1.000	-	-		otm41217
orthoMCL	1	0.900	-	-		OOG6_106608
Panther	1	1.100	-	-	O	PTHR13568
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4200
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770