Protein Alignment Mec2 and PHB2

DIOPT Version :9

• Sequence 1: NP_573357.1
• Gene: Mec2 / 32905
• FlyBaseID: FBgn0030993
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_011747.2
• Gene: PHB2 / 853146
• SGDID: S000003463
• Length: 310
• Species: Saccharomyces cerevisiae
• Alignment Length: 294
• Identity: 72/294 - (24%)
• Similarity: 120/294 - (40%)
• Gaps: 60/294 - (20%)

  Fly    43 RVPGTTQQY-------------RGFKTSENEPKGCMEWVVTLFSVLIFIITSPIAIFI---CFKV 91
            |.||..|:|             .|.:.....|:|....:..|      ::....|:||   .|.|
Yeast     3 RSPGEFQRYAKAFQKQLSKVQQTGGRGQVPSPRGAFAGLGGL------LLLGGGALFINNALFNV 61

  Fly    92 VAEYERAIIF-RLGRLSGGARGPGMFFILPCIDEYRKVDLRTVTFNVPQQEMLTKDSVTVTVDAV 155
            ...: |||:: |:..:|......|..||.|.:|.....|:|....||..... |||...|.:...
Yeast    62 DGGH-RAIVYSRIHGVSSRIFNEGTHFIFPWLDTPIIYDVRAKPRNVASLTG-TKDLQMVNITCR 124

  Fly   156 VYYRISDPLYAVIQV--------EDYSMSTRLLAA---TTLRNIVGTRNLSELLTERETLAHNMQ 209
            |   :|.|  .|:|:        :||  ..|:|.:   ..|:.:|...|.|:|:|:||.::..::
Yeast   125 V---LSRP--DVVQLPTIYRTLGQDY--DERVLPSIVNEVLKAVVAQFNASQLITQREKVSRLIR 182

  Fly   210 ATLDEATEPWGVMVERVEIKDVSLPVSMQRAMAAEAEAARDA--------------RAKVIAAEG 260
            ..|......:.::::.|.|..::.......|:.|:..|.:||              :..|:.|:|
Yeast   183 ENLVRRASKFNILLDDVSITYMTFSPEFTNAVEAKQIAQQDAQRAAFVVDKARQEKQGMVVRAQG 247

  Fly   261 EKKSATALKEASDVISASPSALQLRYLQTLSSIS 294
            |.|||..:.||   |..|...::|:.|.|...|:
Yeast   248 EAKSAELIGEA---IKKSRDYVELKRLDTARDIA 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	PHB	88..238	CDD:214581	40/161 (25%)
		SPFH_like	107..314	CDD:302763	54/213 (25%)
PHB2	NP_011747.2	SPFH_prohibitin	58..252	CDD:259799	50/202 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810