DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mec2 and stom

DIOPT Version :9

Sequence 1:	NP_573357.1	Gene:	Mec2 / 32905	FlyBaseID:	FBgn0030993	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	XP_017208322.1	Gene:	stom / 81534	ZFINID:	ZDB-GENE-980526-486	Length:	305	Species:	Danio rerio

Alignment Length:	253	Identity:	160/253 - (63%)
Similarity:	214/253 - (84%)	Gaps:	1/253 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 GCMEWVVTLFSVLIFIITSPIAIFICFKVVAEYERAIIFRLGR-LSGGARGPGMFFILPCIDEYR 126
            |...|::.:||:|:.::|.|::|::|.|:|.|||||||||||| |.|||:|||:||||||.|.:.
Zfish    51 GLCGWILVIFSILLTLLTLPLSIWMCIKIVKEYERAIIFRLGRILRGGAKGPGLFFILPCTDSFI 115

  Fly   127 KVDLRTVTFNVPQQEMLTKDSVTVTVDAVVYYRISDPLYAVIQVEDYSMSTRLLAATTLRNIVGT 191
            .||:||:||::|.||:||||||||:||.|||||:.:...||..:.:...:|||||.|||||::||
Zfish   116 NVDMRTITFDIPPQEVLTKDSVTVSVDGVVYYRVQNATLAVANITNADAATRLLAQTTLRNVLGT 180

  Fly   192 RNLSELLTERETLAHNMQATLDEATEPWGVMVERVEIKDVSLPVSMQRAMAAEAEAARDARAKVI 256
            :||:|:|::||.:||:||:|||:||:.||:.|||||||||.||:.:||||||||||:|:||||||
Zfish   181 KNLAEILSDREEIAHSMQSTLDDATDDWGIKVERVEIKDVKLPLQLQRAMAAEAEASREARAKVI 245

  Fly   257 AAEGEKKSATALKEASDVISASPSALQLRYLQTLSSISAEKNSTIIFPLPMELLTPYL 314
            |||||..::.||||||.||:.|||||||||||||::|:||||||||||||::::..:|
Zfish   246 AAEGEMNASRALKEASLVIAESPSALQLRYLQTLNTIAAEKNSTIIFPLPIDMMQSFL 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	PHB	88..238	CDD:214581	95/150 (63%)
Mec2	NP_573357.1	SPFH_like	107..314	CDD:302763	135/206 (66%)
stom	XP_017208322.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9274
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54926
OrthoDB	1	1.010	-	-		D1062075at2759
OrthoFinder	1	1.000	-	-		FOG0000760
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100539
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.690