DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mec2 and stoml1

DIOPT Version :9

Sequence 1:	NP_573357.1	Gene:	Mec2 / 32905	FlyBaseID:	FBgn0030993	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001103502.1	Gene:	stoml1 / 563294	ZFINID:	ZDB-GENE-070209-241	Length:	410	Species:	Danio rerio

Alignment Length:	229	Identity:	79/229 - (34%)
Similarity:	127/229 - (55%)	Gaps:	21/229 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 GPASSTAYM-VNMGAAGMAPEPAL---RVP--GTTQQYRGF------KTSENE----PKGCMEW- 67
            |.:|...|. ::.|.:|....|.|   ..|  .:...:||.      |..:|:    .:|.:.|
Zfish     5 GKSSGYEYQCLSQGESGYGETPGLFSSHSPFNNSHHDHRGHSFDYVPKVHQNDYTDKSQGLLSWL 69

  Fly    68 ---VVTLFSVLIFIITSPIAIFICFKVVAEYERAIIFRLGRLSGGARGPGMFFILPCIDEYRKVD 129
               :||....|...:|.||:.:...|||..|||.::|||||:. ..:|||:..|||.||::::||
Zfish    70 CNLIVTFLVFLFTFVTFPISGWFVLKVVPNYERVVVFRLGRIR-PPKGPGVVLILPFIDQWQRVD 133

  Fly   130 LRTVTFNVPQQEMLTKDSVTVTVDAVVYYRISDPLYAVIQVEDYSMSTRLLAATTLRNIVGTRNL 194
            |||..||:|..::.||||..|:|.|.:.:||..|:.:|:.|:|.:.||||.|...:...:..::|
Zfish   134 LRTRAFNIPPCKVCTKDSGLVSVGADIQFRIWSPVMSVVAVQDLNSSTRLTAQNAMMTSLSKKSL 198

  Fly   195 SELLTERETLAHNMQATLDEATEPWGVMVERVEI 228
            .|:.|:|..|..::...::|.|:|||:.|:|||:
Zfish   199 REIQTDRLKLGEHLGMDMNEMTKPWGLEVDRVEL 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	PHB	88..238	CDD:214581	59/141 (42%)
Mec2	NP_573357.1	SPFH_like	107..314	CDD:302763	48/122 (39%)
stoml1	NP_001103502.1	PHB	94..232	CDD:214581	58/138 (42%)
		SPFH_SLP-1	109..239	CDD:259814	50/125 (40%)
		SCP2	301..405	CDD:280250
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062075at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820