Protein Alignment Mec2 and nphs2

DIOPT Version :10

• Sequence 1: NP_573357.1
• Gene: Mec2 / 32905
• FlyBaseID: FBgn0030993
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001018155.2
• Gene: nphs2 / 557914
• ZFINID: ZDB-GENE-051102-2
• Length: 391
• Species: Danio rerio
• Alignment Length: 352
• Identity: 110/352 - (31%)
• Similarity: 178/352 - (50%)
• Gaps: 22/352 - (6%)

  Fly     2 EPH--QDSPVYANYEDMRNSGPASSTAYMVNMGAAGMAPEPALRVPGTTQQYRGFKTSENEPKGC 64
            |||  ::..|....|:........|::.:||:.:.      ..|:....::......:|...:|.
Zfish    47 EPHKRKEKLVTTEEEEEAKDAQIISSSTVVNVDSV------RERIKEEREELLALLETEGPGEGL 105

  Fly    65 ME---------WVVTLFSVLIFIITSPIAIFICFKVVAEYERAIIFRLGR-LSGGARGPGMFFIL 119
            .:         .:|.:.||:|..:  ||:::.|.|:|.|:|||:.||||. |....||||:.|.|
Zfish   106 KKKYLGVCELLLIVLVLSVVILFL--PISVWFCVKIVREHERAVKFRLGHLLKKRPRGPGLMFYL 168

  Fly   120 PCIDEYRKVDLRTVTFNVPQQEMLTKDSVTVTVDAVVYYRISDPLYAVIQVEDYSMSTRLLAATT 184
            |.:|....||:|.....:|...::|||.|...|.||.||||.:...............:.|...:
Zfish   169 PFLDVCHIVDIRLQILKIPPHMVVTKDLVCTEVTAVCYYRIENVSVCYSSFASIPDVMQALTQVS 233

  Fly   185 LRNIVGTRNLSELLTERETLAHNMQATLDEATEPWGVMVERVEIKDVSLPVSMQRAMAAEAEAAR 249
            :|.|:.....:::|.:|:.:|..:|.|||..|..||:.||:.||::::||..:|...|.||||.|
Zfish   234 VREILAHHAFNDILLDRKRIAQEIQVTLDSGTCRWGIKVEKAEIEEINLPPELQHNFAVEAEARR 298

  Fly   250 DARAKVIAAEGEKKSATALKEASDVISASPSALQLRYLQTLSSISAEKNSTIIFPLPMELLTPYL 314
            .|:.|||||||||.:..|||.:.:.:|.||..:.||.||.|.|:.:|: ..::..:|.::||..:
Zfish   299 QAQVKVIAAEGEKAACEALKASVESVSGSPLVMHLRLLQLLHSLRSEQ-PAVVLNIPPDVLTQSI 362

  Fly   315 AKYAHLMGPPPELKQSPEKSDNIVLDA 341
             ..|.|..|..:...:...||:...|:
Zfish   363 -DLASLTRPANQSMTTCHGSDDGTKDS 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	SPFH_like	107..314	CDD:473137	75/206 (36%)
nphs2	NP_001018155.2	SPFH_like	134..356	CDD:473137	85/222 (38%)