DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mec2 and l(2)37Cc

DIOPT Version :9

Sequence 1:NP_573357.1 Gene:Mec2 / 32905 FlyBaseID:FBgn0030993 Length:350 Species:Drosophila melanogaster
Sequence 2:NP_001163012.2 Gene:l(2)37Cc / 49168 FlyBaseID:FBgn0002031 Length:276 Species:Drosophila melanogaster


Alignment Length:219 Identity:55/219 - (25%)
Similarity:98/219 - (44%) Gaps:26/219 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    97 RAIIF-RLGRLSGGARGPGMFFILPCIDEYRKVDLRTVTFNVPQQEMLT--KDSVTVTVDAVVYY 158
            ||:|| |...:.....|.|..|.:|.:......|:|:...|||   ::|  ||...|.:...:.|
  Fly    35 RAVIFDRFTGIKENVVGEGTHFFIPWVQRPIIFDIRSQPRNVP---VITGSKDLQNVNITLRILY 96

  Fly   159 R-ISDPLYAVIQVEDYSMSTRLL---AATTLRNIVGTRNLSELLTERETLAHNMQATLDEATEPW 219
            | |.|.|..:..:.......|:|   |...|:.:|...:..||:|:||.::..:...|....:.:
  Fly    97 RPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAVVAQFDAGELITQREMVSQRVSQELTVRAKQF 161

  Fly   220 GVMVERVEI------KDVSLPVSMQRAMAAEAEAAR--------DARAKVIAAEGEKKSATALKE 270
            |.:::.:.:      ::.:|.|.|::....|||.||        ...|.:|:|||:.::|..|  
  Fly   162 GFILDDISLTHLTFGREFTLAVEMKQVAQQEAEKARFVVEKAEQQKLASIISAEGDAEAAGLL-- 224

  Fly   271 ASDVISASPSALQLRYLQTLSSIS 294
            |.....|....::||.::....|:
  Fly   225 AKSFGEAGDGLVELRRIEAAEDIA 248

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Mec2NP_573357.1 PHB 88..238 CDD:214581 37/153 (24%)
SPFH_like 107..314 CDD:302763 50/208 (24%)
l(2)37CcNP_001163012.2 SPFH_prohibitin 27..221 CDD:259799 48/188 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0330
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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