Protein Alignment Mec2 and STOML2

DIOPT Version :10

• Sequence 1: NP_573357.1
• Gene: Mec2 / 32905
• FlyBaseID: FBgn0030993
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_038470.1
• Gene: STOML2 / 30968
• HGNCID: 14559
• Length: 356
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 81/288 - (28%)
• Similarity: 138/288 - (47%)
• Gaps: 53/288 - (18%)

  Fly    92 VAEYERAIIFRLGRLSGGARGPGMFFILPCIDEYRKV-DLRTVTFNVPQQEMLTKDSVTVTVDAV 155
            |.:.|..::.|:||.. ....||:..::|.:|..|.| .|:.:..|||:|..:|.|:||:.:|.|
Human    41 VPQQEAWVVERMGRFH-RILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGV 104

  Fly   156 VYYRISDPLYAVIQVEDYSMSTRLLAATTLRNIVGTRNLSELLTERETLAHNMQATLDEATEPWG 220
            :|.||.||..|...|||...:...||.||:|:.:|..:|.::..|||:|..::...:::|.:.||
Human   105 LYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWG 169

  Fly   221 VMVERVEIKDVSLPVSMQRAMAAEAEAARDARAKVIAAEGEKKSA-------------------- 265
            :...|.||||:.:|..::.:|..:.||.|..||.|:.:||.::||
Human   170 IRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKA 234

  Fly   266 ----TALKEASDVIS---ASPSALQL--------------------RYLQTLSSISAEKNSTIIF 303
                .|..|||.|::   |...|:::                    :|:...|.::.:.| ||:.
Human   235 EQINQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSN-TILL 298

  Fly   304 PLPMELLTPYLAKYAHLMGPPPELKQSP 331
            |.....:|..:|:   .||....|.::|
Human   299 PSNPGDVTSMVAQ---AMGVYGALTKAP 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	SPFH_like	107..314	CDD:473137	71/254 (28%)
STOML2	NP_038470.1	HflC	41..300	CDD:440099	74/260 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	321..356		1/3 (33%)