DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mec2 and SPBC16G5.07c

DIOPT Version :9

Sequence 1:	NP_573357.1	Gene:	Mec2 / 32905	FlyBaseID:	FBgn0030993	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_596756.1	Gene:	SPBC16G5.07c / 2539877	PomBaseID:	SPBC16G5.07c	Length:	354	Species:	Schizosaccharomyces pombe

Alignment Length:	208	Identity:	64/208 - (30%)
Similarity:	112/208 - (53%)	Gaps:	4/208 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 KVVAEYERAIIFRLGRLSGGARGPGMFFILPCIDEYRKV-DLRTVTFNVPQQEMLTKDSVTVTVD 153
            |.|.:....::.|:||.| ....||:.|:.|.||:...: .|:.....:|.|..:|.|:|::.:|
pombe    54 KFVPQQVAYVVERMGRFS-RILTPGVAFLAPIIDKIAYIHSLKERALEIPTQSAITLDNVSLGLD 117

  Fly   154 AVVYYRISDPLYAVIQVEDYSMSTRLLAATTLRNIVGTRNLSELLTERETLAHNMQATLDEATEP 218
            .|:|.::.||..|...|||...:...||.||:|:.:|...|..:|.||::|..::...:::|.|.
pombe   118 GVLYIQVYDPYKASYGVEDADYAISQLAQTTMRSEIGRLTLDHVLRERQSLNIHITDAINKAAES 182

  Fly   219 WGVMVERVEIKDVSLPVSMQRAMAAEAEAARDARAKVIAAEGEKKSATALKEASDVISASPSALQ 283
            ||:...|.||:|:..|.|:..||..:..|.|..||:::.:||::::|..:.|.........|..|
pombe   183 WGIRCLRHEIRDIRPPESVVMAMHQQVSAERQKRAEILESEGKRQAAINVAEGDKQAEILDSEGQ 247

  Fly   284 LRYLQTLSSISAE 296
              .::|::|..||
pombe   248 --KIKTINSALAE 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	PHB	88..238	CDD:214581	48/148 (32%)
Mec2	NP_573357.1	SPFH_like	107..314	CDD:302763	59/191 (31%)
SPBC16G5.07c	NP_596756.1	PHB	52..209	CDD:214581	50/155 (32%)
		SPFH_paraslipin	89..199	CDD:259811	34/109 (31%)
		Band_7_C	275..337	CDD:292817
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810