Protein Alignment Mec2 and Phb1

DIOPT Version :10

• Sequence 1: NP_573357.1
• Gene: Mec2 / 32905
• FlyBaseID: FBgn0030993
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_114039.1
• Gene: Phb1 / 25344
• RGDID: 3322
• Length: 272
• Species: Rattus norvegicus
• Alignment Length: 245
• Identity: 64/245 - (26%)
• Similarity: 114/245 - (46%)
• Gaps: 43/245 - (17%)

  Fly    97 RAIIF-RLGRLSGGARGPGMFFILPCIDEYRKVDLRTVTFNVPQQEMLT--KDSVTVTVDAVVYY 158
            ||:|| |...:.....|.|..|::|.:.:....|.|:...|||   ::|  ||...|.:...:.:
  Rat    35 RAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVP---VITGSKDLQNVNITLRILF 96

  Fly   159 R-ISDPL---YAVIQVEDYSMSTRLLAATT---LRNIVGTRNLSELLTERETLAHNMQATLDEAT 216
            | ::..|   |..|. |||  ..|:|.:.|   |:::|...:..||:|:||.::..:...|.|..
  Rat    97 RPVASQLPRIYTSIG-EDY--DERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERA 158

  Fly   217 EPWGVMVERVEI------KDVSLPVSMQRAMAAEAEAAR--------DARAKVIAAEGEKKSATA 267
            ..:|::::.|.:      |:.:..|..::....|||.||        ..:|.:|:|||:.|:|..
  Rat   159 ATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAEL 223

  Fly   268 LKEASDVISASPSALQLRYLQTLSSI----SAEKNST-------IIFPLP 306
            :  |:.:.:|....::||.|:....|    |..:|.|       ::..||
  Rat   224 I--ANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLP 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	SPFH_like	107..314	CDD:473137	59/234 (25%)
Phb1	NP_114039.1	SPFH_prohibitin	27..221	CDD:259799	52/191 (27%)