Protein Alignment Mec2 and mec-2

DIOPT Version :10

• Sequence 1: NP_573357.1
• Gene: Mec2 / 32905
• FlyBaseID: FBgn0030993
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001368712.1
• Gene: mec-2 / 180826
• WormBaseID: WBGene00003166
• Length: 1239
• Species: Caenorhabditis elegans
• Alignment Length: 284
• Identity: 179/284 - (63%)
• Similarity: 224/284 - (78%)
• Gaps: 4/284 - (1%)

  Fly    63 GCMEWVVTLFSVLIFIITSPIAIFICFKVVAEYERAIIFRLGRL-SGGARGPGMFFILPCIDEYR 126
            |...|::|:.|.|:...|.||:..:|.|||.|||||:||||||| .|||:|||:|||:||||.||
 Worm   115 GVCGWILTILSYLLIFFTLPISACMCIKVVQEYERAVIFRLGRLMPGGAKGPGIFFIVPCIDTYR 179

  Fly   127 KVDLRTVTFNVPQQEMLTKDSVTVTVDAVVYYRISDPLYAVIQVEDYSMSTRLLAATTLRNIVGT 191
            |||||.::|.||.||:|:||||||.||||||:|||:...:|..|||.:.||:|||.||||||:||
 Worm   180 KVDLRVLSFEVPPQEILSKDSVTVAVDAVVYFRISNATISVTNVEDAARSTKLLAQTTLRNILGT 244

  Fly   192 RNLSELLTERETLAHNMQATLDEATEPWGVMVERVEIKDVSLPVSMQRAMAAEAEAARDARAKVI 256
            :.|:|:|::||.::|.||.|||||||||||.|||||:|||.|||.:||||||||||||:||||||
 Worm   245 KTLAEMLSDREAISHQMQTTLDEATEPWGVKVERVEVKDVRLPVQLQRAMAAEAEAAREARAKVI 309

  Fly   257 AAEGEKKSATALKEASDVISASPSALQLRYLQTLSSISAEKNSTIIFPLPMELLTPYLAKYAHLM 321
            .||||:|::.|||||::||:.|||||||||||||:|||||||||||||.|::||:.:|.:....:
 Worm   310 VAEGEQKASRALKEAAEVIAESPSALQLRYLQTLNSISAEKNSTIIFPFPIDLLSAFLQRTPPKV 374

  Fly   322 GPPPELKQSPEKSDNIVLDALDAW 345
            ..||.|   |:|..:..|.....|
 Worm   375 EEPPSL---PKKIRSCCLYKYPDW 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	SPFH_like	107..314	CDD:473137	147/206 (71%)
mec-2	NP_001368712.1	SPFH_stomatin	160..361	CDD:259801	145/200 (73%)
		PTZ00121	<571..>913	CDD:173412