Protein Alignment Mec2 and sto-2

DIOPT Version :10

• Sequence 1: NP_573357.1
• Gene: Mec2 / 32905
• FlyBaseID: FBgn0030993
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001257021.1
• Gene: sto-2 / 180802
• WormBaseID: WBGene00006064
• Length: 375
• Species: Caenorhabditis elegans
• Alignment Length: 367
• Identity: 191/367 - (52%)
• Similarity: 245/367 - (66%)
• Gaps: 58/367 - (15%)

  Fly     2 EPHQD--SPVYANYEDMRNSG--PASST----AYMVNMGAAGMA------------PEPALRVPG 46
            :|.::  ||...|..:..|||  .||||    :..::.|.:|.:            .|..:::|.
 Worm     4 QPSEESASPAPVNPGNSGNSGNRRASSTRISFSDQLDGGDSGDSSSNESERLMESDDEGNIQIPV 68

  Fly    47 TTQQYRG------------FKTSENE--------------PK-----------GCMEWVVTLFSV 74
            .|.|.||            |...|.|              ||           |...|.:...|.
 Worm    69 PTGQPRGRMGRRFTLNPLIFAKEEREARRQSLAQLKLSYYPKHMNPEHYDTGLGFCGWFLMGLSW 133

  Fly    75 LIFIITSPIAIFICFKVVAEYERAIIFRLGRL-SGGARGPGMFFILPCIDEYRKVDLRTVTFNVP 138
            ::.|.|.|::|:.|.|||.|||||:||||||| .|||:|||:||:||||:.|.|||||||:|:||
 Worm   134 IMVISTFPVSIYFCMKVVQEYERAVIFRLGRLIGGGAKGPGIFFVLPCIESYTKVDLRTVSFSVP 198

  Fly   139 QQEMLTKDSVTVTVDAVVYYRISDPLYAVIQVEDYSMSTRLLAATTLRNIVGTRNLSELLTERET 203
            .||:|||||||.:||||:|||||:...:|..||:...||||||.|||||::|||:|||:|::|||
 Worm   199 PQEILTKDSVTTSVDAVIYYRISNATVSVANVENAHHSTRLLAQTTLRNMLGTRSLSEILSDRET 263

  Fly   204 LAHNMQATLDEATEPWGVMVERVEIKDVSLPVSMQRAMAAEAEAARDARAKVIAAEGEKKSATAL 268
            ||.:||..||||||.||:.|||||||||.||:.:||||||||||.|:|||||||||||:|::.||
 Worm   264 LAASMQTILDEATESWGIKVERVEIKDVRLPIQLQRAMAAEAEATREARAKVIAAEGEQKASRAL 328

  Fly   269 KEASDVISASPSALQLRYLQTLSSISAEKNSTIIFPLPMELL 310
            ::|:.||:.||:||||||||||:|::|||||||||||||||:
 Worm   329 RDAASVIAQSPAALQLRYLQTLNSVAAEKNSTIIFPLPMELV 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	SPFH_like	107..314	CDD:473137	144/204 (71%)
sto-2	NP_001257021.1	SPFH_like	168..368	CDD:473137	141/199 (71%)