Protein Alignment Mec2 and unc-1

DIOPT Version :10

• Sequence 1: NP_573357.1
• Gene: Mec2 / 32905
• FlyBaseID: FBgn0030993
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001123162.1
• Gene: unc-1 / 180458
• WormBaseID: WBGene00006741
• Length: 289
• Species: Caenorhabditis elegans
• Alignment Length: 286
• Identity: 159/286 - (55%)
• Similarity: 210/286 - (73%)
• Gaps: 14/286 - (4%)

  Fly    39 EPALRVPGTTQQYRGFKTSENEPKGCMEWVVTLF-------SVLIFIITSPIAIFICFKVVAEYE 96
            ||....|.:.|      .|:.:.....|.:.|:|       |.::.|:|.|.::.:|.||:.|||
 Worm     8 EPQWVTPSSNQ------VSQQDVPPDYETIGTIFGYALQALSWILIIVTFPFSMCVCLKVIKEYE 66

  Fly    97 RAIIFRLGRL-SGGARGPGMFFILPCIDEYRKVDLRTVTFNVPQQEMLTKDSVTVTVDAVVYYRI 160
            |.:|||:||| .||||||||.||:||||.|||:|||.|::.||.||:|:||||||:||||||:|.
 Worm    67 RVVIFRIGRLVFGGARGPGMIFIIPCIDTYRKIDLRVVSYAVPPQEILSKDSVTVSVDAVVYFRT 131

  Fly   161 SDPLYAVIQVEDYSMSTRLLAATTLRNIVGTRNLSELLTERETLAHNMQATLDEATEPWGVMVER 225
            |||:.:|..|:|...||:|||.|||||.:|.:.|:|:|||||.:|...:..|||.||.|||.|||
 Worm   132 SDPIASVNNVDDAIYSTKLLAQTTLRNALGMKTLTEMLTEREAIAQLCETILDEGTEHWGVKVER 196

  Fly   226 VEIKDVSLPVSMQRAMAAEAEAARDARAKVIAAEGEKKSATALKEASDVISASPSALQLRYLQTL 290
            ||:||:.||..:.|||||||||||:|||||:|||||:|::.|||||:|||.|:|.|||||:||.|
 Worm   197 VEVKDIRLPQQLTRAMAAEAEAAREARAKVVAAEGEQKASRALKEAADVIQANPVALQLRHLQAL 261

  Fly   291 SSISAEKNSTIIFPLPMELLTPYLAK 316
            :||:||.||||:||:|:|:...::.|
 Worm   262 NSIAAEHNSTIVFPVPVEMFGAFMKK 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	SPFH_like	107..314	CDD:473137	133/206 (65%)
unc-1	NP_001123162.1	SPFH_like	79..279	CDD:473137	132/199 (66%)