Protein Alignment Mec2 and unc-24

DIOPT Version :10

• Sequence 1: NP_573357.1
• Gene: Mec2 / 32905
• FlyBaseID: FBgn0030993
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_001355386.1
• Gene: unc-24 / 177594
• WormBaseID: WBGene00006761
• Length: 443
• Species: Caenorhabditis elegans
• Alignment Length: 324
• Identity: 83/324 - (25%)
• Similarity: 142/324 - (43%)
• Gaps: 65/324 - (20%)

  Fly    10 YANYEDMRNSGPASSTAYMVNMGAAGMAPEPALRVPGTTQQYRGFKTSEN---------EPKGCM 65
            ||.|.|:...|      ||          .||.:......:|..|..:.:         :|...:
 Worm    59 YAPYNDLDKMG------YM----------GPARQGMMLGNKYGNFTYTRDYGVNMEDDIKPLSAI 107

  Fly    66 EWVVTLFSVLIFIITSPIAIFICFKVVAEYERAIIFRLGRLSGGARGPGMFFILPCIDEYRKVDL 130
            |.::...|.|..::|.|:::....|.::..|:.::.|||| :...||||:..::||||...||.:
 Worm   108 ELLIFCVSFLFVVMTMPLSLLFALKFISTSEKLVVLRLGR-AQKTRGPGITLVIPCIDTTHKVTM 171

  Fly   131 RTVTFNVPQQEMLTKDSVTVTVDAVVYYRISDPLYAVIQVEDYSMSTRLLAATTLRNIVGTRNLS 195
            ....||||..:::|.|...|.:.|.|:.:|.||:.||..|:|.:.|.|.||.|.|...:..:.:.
 Worm   172 SITAFNVPPLQIITTDRGLVELGATVFLKIRDPIAAVCGVQDRNASVRTLANTMLYRYISKKRIC 236

  Fly   196 ELLTERETLAHNMQATLDEATEPWGVMVERVEIKDVSLPVSMQR-AMAAEAEAAR-DAR------ 252
            :             ..|...|..:||.:..|||.||.:....:. .|:|.:..|: ||.
 Worm   237 D-------------DELGSFTCQFGVEITDVEISDVKIVKEGENMGMSALSSVAKSDAGQQLWQV 288

  Fly   253 --------AKVIAAEGEKKSATALKEASDVISASPS----------ALQLRYLQTLSSISAEKN 298
                    ||..|||.:.|....|.:.|||.|.|.:          ::.:.:|.:::|::.:::
 Worm   289 IGPVFEDFAKECAAEEKAKENAPLVDLSDVPSTSAAGTSTDTPNIPSIDIDHLISVASLAMDEH 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	SPFH_like	107..314	CDD:473137	60/218 (28%)
unc-24	NP_001355386.1	SPFH_like	146..263	CDD:473137	43/130 (33%)
		SCP2	357..439	CDD:442486