Protein Alignment Mec2 and phb-2

DIOPT Version :10

• Sequence 1: NP_573357.1
• Gene: Mec2 / 32905
• FlyBaseID: FBgn0030993
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_495250.2
• Gene: phb-2 / 174034
• WormBaseID: WBGene00004015
• Length: 294
• Species: Caenorhabditis elegans
• Alignment Length: 252
• Identity: 63/252 - (25%)
• Similarity: 114/252 - (45%)
• Gaps: 31/252 - (12%)

  Fly    89 FKVVAEYERAIIF-RLGRLSGGARGPGMFFILPCIDEYRKVDLRTVTFNVPQQEMLTKDSVTVTV 152
            |.|.|.: |||:| |:|.||......|:.|.:|........|:|... |..:....:||...|.:
 Worm    41 FTVEAGH-RAIMFNRIGGLSTDLYKEGLHFRIPWFQYPIIYDIRARP-NQIRSPTGSKDLQMVNI 103

  Fly   153 DAVVYYRIS-DPLYAVIQVEDYSMSTRLLAA---TTLRNIVGTRNLSELLTERETLAHNMQATLD 213
            ...|..|.: :.|..:.:....:...|:|.:   ..|:.:|...|.|:|:|:|:.::..::.||.
 Worm   104 GLRVLSRPNPEHLVHIYRTLGQNWEERVLPSICNEVLKGVVAKFNASQLITQRQQVSMLVRKTLI 168

  Fly   214 EATEPWGVMVERVEIKDVSLPVSMQRAMAAEAEAARDA--------------RAKVIAAEGEKKS 264
            |....:.::::.|.:.:::.......|:.|:..||::|              :.|::.||||.:|
 Worm   169 ERALDFNIILDDVSLTELAFSPQYSAAVEAKQVAAQEAQRATFYVERAKQQKQEKIVQAEGEAES 233

  Fly   265 ATALKEASDVISASPSALQLRYL---QTLSSISAEKNSTIIFPLPMELL----TPYL 314
            |..|.||   :...|..|:||.:   |.::.|.:|..:....|....:|    |.||
 Worm   234 AKLLGEA---MKNDPGFLKLRKIRAAQKIARIVSESGNKTYLPTGGLMLNIADTDYL 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	SPFH_like	107..314	CDD:473137	51/231 (22%)
phb-2	NP_495250.2	SPFH_prohibitin	40..234	CDD:259799	46/194 (24%)
		PRK11029	<205..287	CDD:182913	21/84 (25%)