Protein Alignment Mec2 and STOML3

DIOPT Version :10

• Sequence 1: NP_573357.1
• Gene: Mec2 / 32905
• FlyBaseID: FBgn0030993
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_660329.1
• Gene: STOML3 / 161003
• HGNCID: 19420
• Length: 291
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 150/263 - (57%)
• Similarity: 196/263 - (74%)
• Gaps: 1/263 - (0%)

  Fly    49 QQYRGFKTSENEPKGCMEWVVTLFSVLIFIITSPIAIFICFKVVAEYERAIIFRLGRLSGG-ARG 112
            |....|....|:..|...|::...|.|:.|||.||:|::|.|::.|||||::|||||:... |:|
Human    11 QDKENFVGVNNKRLGVCGWILFSLSFLLVIITFPISIWMCLKIIKEYERAVVFRLGRIQADKAKG 75

  Fly   113 PGMFFILPCIDEYRKVDLRTVTFNVPQQEMLTKDSVTVTVDAVVYYRISDPLYAVIQVEDYSMST 177
            ||:..:|||||.:.||||||||.|:|.||:||:||||..||.||||||...:.||..|.|...:|
Human    76 PGLILVLPCIDVFVKVDLRTVTCNIPPQEILTRDSVTTQVDGVVYYRIYSAVSAVANVNDVHQAT 140

  Fly   178 RLLAATTLRNIVGTRNLSELLTERETLAHNMQATLDEATEPWGVMVERVEIKDVSLPVSMQRAMA 242
            .|||.|||||::||:.||::|..||.:||::|..||:|||.||:.|.|||||||.:||.:||:||
Human   141 FLLAQTTLRNVLGTQTLSQILAGREEIAHSIQTLLDDATELWGIRVARVEIKDVRIPVQLQRSMA 205

  Fly   243 AEAEAARDARAKVIAAEGEKKSATALKEASDVISASPSALQLRYLQTLSSISAEKNSTIIFPLPM 307
            |||||.|:|||||:|||||..::.:||.||.|::.||.|||||||||||:::.||||||:|||||
Human   206 AEAEATREARAKVLAAEGEMNASKSLKSASMVLAESPIALQLRYLQTLSTVATEKNSTIVFPLPM 270

  Fly   308 ELL 310
            .:|
Human   271 NIL 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	SPFH_like	107..314	CDD:473137	125/205 (61%)
STOML3	NP_660329.1	SPFH_like	73..271	CDD:473137	123/197 (62%)