Protein Alignment Mec2 and Stom

DIOPT Version :9

• Sequence 1: NP_573357.1
• Gene: Mec2 / 32905
• FlyBaseID: FBgn0030993
• Length: 350
• Species: Drosophila melanogaster
• Sequence 2: NP_038543.1
• Gene: Stom / 13830
• MGIID: 95403
• Length: 284
• Species: Mus musculus
• Alignment Length: 269
• Identity: 163/269 - (60%)
• Similarity: 211/269 - (78%)
• Gaps: 7/269 - (2%)

  Fly    43 RVPGTTQQYRGFKTSENEPKGCMEWVVTLFSVLIFIITSPIAIFICFKVVAEYERAIIFRLGR-L 106
            |:|      ..|:.:.....|...|::...|....|||.||:|:||.|:|.||||.||||||| |
Mouse    14 RIP------ESFRENSKTELGACGWILVAASFFFVIITFPISIWICIKIVKEYERVIIFRLGRIL 72

  Fly   107 SGGARGPGMFFILPCIDEYRKVDLRTVTFNVPQQEMLTKDSVTVTVDAVVYYRISDPLYAVIQVE 171
            .|||:|||:||||||.|...|||:||::|::|.||:|||||||::||.|||||:.:...||..:.
Mouse    73 QGGAKGPGLFFILPCTDSLIKVDMRTISFDIPPQEVLTKDSVTISVDGVVYYRVQNATLAVANIT 137

  Fly   172 DYSMSTRLLAATTLRNIVGTRNLSELLTERETLAHNMQATLDEATEPWGVMVERVEIKDVSLPVS 236
            :...:|||||.|||||.:||:|||::|::||.:||:||:|||:||:.||:.|||||||||.|||.
Mouse   138 NADSATRLLAQTTLRNALGTKNLSQILSDREEIAHHMQSTLDDATDDWGIKVERVEIKDVKLPVQ 202

  Fly   237 MQRAMAAEAEAARDARAKVIAAEGEKKSATALKEASDVISASPSALQLRYLQTLSSISAEKNSTI 301
            :||||||||||||:|||||||||||..::.||||||.||:.||:||||||||||::|:|||||||
Mouse   203 LQRAMAAEAEAAREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTI 267

  Fly   302 IFPLPMELL 310
            :||||:::|
Mouse   268 VFPLPVDML 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mec2	NP_573357.1	PHB	88..238	CDD:214581	94/150 (63%)
		SPFH_like	107..314	CDD:302763	135/204 (66%)
Stom	NP_038543.1	PHB	53..204	CDD:214581	94/150 (63%)
		SPFH_stomatin	73..274	CDD:259801	134/200 (67%)
		Required for homooligomerization. /evidence=ECO:0000250	265..273		6/7 (86%)
		Required for lipid raft association. /evidence=ECO:0000250	267..269		1/1 (100%)
		Interaction with LANCL1. /evidence=ECO:0000250	273..284		1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I9581
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54926
OrthoDB	1	1.010	-	-		D1062075at2759
OrthoFinder	1	1.000	-	-		FOG0000760
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100539
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.690